What Are Parvovirus Symptoms?

Parvovirus is a non-encapsulated, single-stranded, DNA virus. Canines can be infected with small antigen transfers and natural mutations.

Parvovirus

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Isolate the disease and immediately raise it. Prevent sick dogs and sick dog breeders from coming into contact with healthy dogs, and repeatedly disinfect kennels and venues with 2% fire alkali water or 10-20% bleaching powder. It is important to remind that if you have a puppies in your family, even if the environment has been disinfected, do not take home other puppies that have not been vaccinated, or they will be infected soon.

Clinically, it is mainly symptomatic treatment combined with high immunity serum and monoclonal antibody therapy (lighter for early stage disease, monoclonal antibody effect is higher than high immunity serum). The cure rate for adult dogs is higher than for puppies, and the cure rate for crossbreed dogs is higher than for pedigree dogs (mostly pedigree dogs are obtained from inbreeding and have low immunity).

Parvovirus is the second most common disease in dogs and is characterized by a rapid onset and a high mortality rate.

Parvoviruses are endemic, currently ^[2]

Dogs develop physical symptoms within 3-14 days after exposure to parvovirus, with an average onset time of 5-7 days. Clinical symptoms include: loss of appetite, depression, fever, vomiting, diarrhea, and fecal odors specific to canine parvovirus. Adult dogs (dogs older than twelve months) have a low incidence. If they are not very pure dogs or inbreeding adult dogs, they generally do not show obvious symptoms. They only show a certain stinky smell in the feces and a loss of appetite. No exacerbations may require no treatment.

Dogs infected with canine parvovirus can be clinically divided into enteritis and myocarditis.

Enteritis type: The incubation period of natural infection is 7 to 14 days. At the beginning of the illness, fever appears. The body temperature can reach above 40 ° C. The spirit is depressed, not eating, and vomiting. The initial vomit is undigested food and white foam (stomach acid), followed by mucus and yellow-green liquid. Diarrhea started one day after the onset. At the beginning of the disease, the feces were thin or semi-shaped, with a certain fishy smell. As the disease progresses, the stool becomes dark green or yellow jelly. Subsequently, the feces were ketchup or coffee-colored, the smell was stinky, the number of bowel movements was irregular, and the symptoms were severe after the emergency. Symptoms of patients with bloody stools include sunken eyes, dry nose, general weakness, and significant weight loss, accompanied by pale conjunctiva, oral mucosa, and severe symptoms of anemia. If the disease is not treated in time, it can cause intestinal toxin absorption and poisoning. Until shock and death. Occasionally, the following cases occur in dogs: the stool is transparent water with bloodshot blood and a stench smell, or the stool is a thin white stool.

Myocarditis type: It is more common in puppies around 40 days of age. The sick dogs have no obvious clinical symptoms, some have sudden breathing difficulties, heart failure, and die within a short time; some sick dogs die after mild diarrhea. Canine parvovirus myocarditis type is caused by canine parvovirus attacking myocardial cells of dogs and can destroy dogs' myocardial cells in a short time. Then the dog appeared

First, immunizations should be done normally. The domestic dog six-line vaccine is clinically found to have low immune protection. It is recommended to inject the imported canine double vaccine. Puppies can be injected under 45 days of health. Depending on the brand, one or two injections are required. The two vaccines are canine parvovirus and canine distemper vaccine. This is the most basic vaccine for dogs. It is very important in any case and the price is not high, so please inject the majority of dog owners. The immunization period is 7-15 days after the vaccine injection. Because the dual vaccine is an attenuated vaccine, the dog s immunity is extremely weak during this time. Do not bathe the dog, do not go out, and try to ventilate and keep Hygienic environment for dogs. This is the most important. ^[1]

Second, when the dog outbreak of this disease, should be isolated in time. For kennels and feeding equipment, use 2% to 4% caustic soda, 1% formalin, 0.5% peroxyacetic acid or 5% to 6%. Repeated disinfection of sodium hypochlorite.

Third, use medication appropriately, do not abuse antibiotics and other drugs: please read this paragraph carefully

Canine parvovirus is divided into two types. One can cause female dogs to have difficulty giving birth. This symptom is common to most parvoviruses. Most parvoviruses can cause dystocia and stillbirth to the host. The second is our most common type, which is divided into enteritis type and myocarditis type. Myocarditis type is more common in puppies. The incidence of puppies is quite high, around 10%, no obvious symptoms, early symptoms occasionally vomiting, mild diarrhea, etc., But he died suddenly. When I raised a dog, I unfortunately encountered a myocarditis type. The dog suddenly became particularly stingy, not eating, not drinking water, and thinning, and suddenly improved the next day. On the third morning, he could even eat, but suddenly at noon Violent death. These are some of the features for reference.

The other type is enteritis, which occurs on the second day after the onset of symptoms, mainly vomiting white foam or undigested food, diarrhea, yellow semi-molded stool, with a fishy smell, and some enteritis dogs have diarrhea. White loose stools, a few patients with extremely poor immunity will initially appear as clear liquid with bloodshot stools. According to my experience, it should be shedding of the intestinal mucosa. With the development of the disease, vomiting becomes more serious, vomiting white foam, stools are brown or green jelly-like stools, smelly. Then it developed into the most obvious features: sprayed feces, extremely stink, the color of coffee or green or tomato, caused by intestinal mucosa shedding, caused by intestinal bleeding. Enteritis-type parvovirus is the most important remedy. Enteritis-type parvovirus can cause acidosis, major intestinal bleeding, and intestinal absorption of toxins, so it must be suppressed as soon as possible to stop bleeding. Anti-acidosis drugs are mainly medical sodium bicarbonate, hemostatic injections or other hemostatic drugs. If the symptoms are remedied and the symptoms are alleviated, the chances of recovery are still high, and canine immunity to canine parvovirus for life. The cause of acidosis (the solution drug is omeprazole injection, and the auxiliary drug is 6542 injection). Please see below.

Causes of acidosis: If the dog has not eaten for a long time, the acid in the stomach is secreted and eroded to the stomach wall. The stomach wall loses the protection of the mucosa. As a result, the acid is absorbed and the acidosis is caused. This is only one of the reasons. There are some reasons. But this is the main thing.

(1) Main measures for early use of monoclonal antibodies. According to the degree of dehydration and systemic condition of the dog, the required components and the amount of fluid replacement should be determined. Generally, the volume of intravenous fluid replacement is 60 ml / kg body weight.

Intravenous fluid 5% glucose solution, vitamin C 0.1ml / kg body weight, ATP 0.1ml / kg body weight, slow intravenous drip once, 2 times / day.

During the infusion, the amount of infusion and the speed of infusion must be strictly controlled, and the function of the heart should be paid attention to, otherwise the treatment failure may easily occur.

When the dog shows severe vomiting and diarrhea, dehydration, electrolyte disturbance and acid-base balance should be corrected. Intravenous infusion of lactated Ringer's solution 50-500 ml (PS: more serious, you should ask your doctor to use sodium bicarbonate for injection.), 25 % Glucose solution 5-40 ml, anisodamine hydrochloride (6542) injection 0.3- 1 ml, 2 times a day.

After mid-term acidosis is more serious, 2.5 grams of sodium bicarbonate injection and 1.5 grams of potassium chloride injection can be used. They can be mixed and used together in a solvent (sodium chloride injection), which can solve the problem of acidosis. ^[1]

Intraperitoneal rehydration, such as the intravenous drip of sick dogs is difficult, peritoneal rehydration is feasible, the dosage is 70 ml / kg body weight.

(3) Antibacterial and anti-inflammatory can use various broad-spectrum antibiotics, but do not use it for a long time, in order to prevent the normal intestinal flora from dysregulation, but delay the recovery of intestinal digestive function.

(4) In case of severe vomiting and vomiting, intramuscular injection of Emmaul and Metuberine (Metoprolol) may be 0.3 to 2 ml. Note: Vomiting is mainly caused by excessive secretion of gastric acid in dogs for a long period of time without food. The secretion of gastric acid will also cause the dog's gastrointestinal peristalsis to aggravate the dog's pain. The wrong injection (capsule) is used. Omela wrong can well inhibit gastric acid secretion, 6542 can reduce the gastrointestinal motility of dogs to a certain extent.

(5) Those with obvious anti-shock symptoms can inject 5 to 15 mg of dexamethasone (flumetasone) or 0.3 to 1 ml of anisodamine hydrochloride (6542) injection.

(6) Strengthen nursing care to keep warm the sick dogs. During the treatment period, fast and water should be absent, and digestible feed should be given at the time of recovery to reduce gastrointestinal burden and improve cure rate.