What Is a Cerebral Meningioma?
Convex meningiomas
- Western Medicine Name
- Meningiomas
- English name
- Meningiomas
- Affiliated Department
- Surgery-Neurosurgery
- Contagious
- Non-contagious
| Xu Geng | (Chief physician) | Department of Neurosurgery, Xuanwu Hospital, Capital Medical University |
| Xu Jianyu | (Attending physician) | Department of Neurosurgery, Xuanwu Hospital, Capital Medical University |
- Meningiomas are derivatives derived from the meninges and meninges. The incidence rate is 19.2% of intracranial tumors, ranking second. Females: males are 2: 1. The peak age of onset is 45 years, and children are rare. Many asymptomatic meningiomas are found by chance. Multiple meningiomas are occasionally visible, and family history is reported in the literature. 50% is located next to the sagittal sinus, the other is the convex surface of the brain, and it is more common next to the sickle of the brain, followed by sphenoid condyles, saddle nodules, olfactory sulcus, cerebellar pontine angle and cerebellar tentacles. Few people grow in the ventricle. Can also be seen epidurally. Occasionally seen elsewhere.
Meningioma disease classification
Meningioma
- Convex meningiomas
- Parasinus meningioma
- Falx meningioma
- Intraventricular meningiomas
- Multiple meningioma
Meningiomas
- Sphenoid ridge meningiomas
- Saddle nodule meningioma
- Olfactory sulcus meningioma
- Middle cranial meningioma
- Pontine cerebellar meningioma
- Cerebellar meningioma
- Rock bone-slope meningioma
- Occipital foramen meningiomas
- Cavernous sinus meningiomas
- Orbital and cranio-orbital meningioma
Meningiomas meningiosarcoma
Meningiomas malignant meningiomas
Causes of meningiomas
- The occurrence of meningiomas may be related to certain changes in the internal environment and genetic mutations, not caused by a single factor, and may be related to factors such as traumatic brain injury, radiation exposure, viral infection, and combined bilateral acoustic neuroma. Arachnoid cells are generally thought to divide very slowly. Appeal factors accelerate cell division and may be an important early stage of cell degeneration.
Meningioma pathophysiology
- Meningiomas grow in a spherical shape and have clear boundaries with brain tissue. Common meningiomas have the following types:
- Endothelial
- Fibroblast
- Grit type
- Vascular type
- Hybrid (transition type)
- Malignant meningioma
- Meningeal sarcoma
Meningioma clinical manifestations
- Meningiomas are benign tumors with slow growth and long duration. Due to the tumescent growth of the tumor, patients often have headaches and epilepsy as the first symptoms. Depending on the location of the tumor, vision, vision, olfactory or hearing disorders, and limb movement disorders can also occur. In the elderly, epilepsy is more common as the first symptom. The symptoms of increased intracranial pressure are not obvious, especially in elderly patients. With the increasing popularity of CT examinations, many patients have only mild headaches, and even accidentally found meningioma by CT scan. Due to the slow growth of tumors, tumors often grow very large, and clinical symptoms are not serious. Meningiomas near the skull often cause bone changes.
Diagnosis and differential diagnosis of meningiomas
CT CT scan of meningioma head
- Typical meningiomas, in unenhanced CT scans, present as isolated isodensity or high-density mass lesions. Its base is wide, the density is uniform, the edges are clear, and calcification is visible in the tumor. After enhancement, tumors were significantly enhanced, and meningeal tail signs were seen.
Meningioma magnetic resonance scan
- For the same patient, it is best to perform a comparative analysis of CT and MRI at the same time to obtain a more accurate qualitative diagnosis.
Meningioma cerebral angiography
- All types of meningiomas are rich in vascular structure. DSA and superselective angiography are useful for confirming the vascular structure of tumors, the degree of tumor richness in blood vessels, the displacement of major cerebral vessels, and the relationship between tumors and large dural sinuses The degree of openness of the sinuses all provide essential details. At the same time, the angiography technology also provides help for preoperative embolization of the supply arteries and reduces intraoperative bleeding.
Meningioma disease treatment
Meningioma resection
- Surgical removal of meningioma is the most effective treatment. With the development of microsurgery technology, the surgical effect of meningiomas has been continuously improved, enabling most patients to be cured.
Meningiomas radiotherapy
- Benign meningiomas have excellent resection results, but due to their growth location, about 17% to 50% of meningiomas cannot be resected, and there are also a few malignant meningiomas that cannot be resected. The above two cases require radiotherapy after surgical resection. Malignant meningioma and hemangioperiodous meningioma are sensitive to radiotherapy and the effect is positive. There are still different opinions on the effectiveness of general radiotherapy for benign tumors. [1]
Other treatments for meningiomas
- Hormonal therapy, molecular biology therapy, traditional Chinese medicine treatment, etc.
Meningioma Prognosis
- As with any tumor, meningiomas undergo surgery for the first time. If some tumors remain in the primary site, tumor recurrence may occur. The preferred method for managing recurrent meningiomas is still surgical resection. Many studies have shown that radiation therapy is effective for meningioma that has not been completely removed, recurrent meningioma that cannot be operated on, or some special types of meningioma.
- The average postoperative survival time of meningiomas is 9 years, and the postoperative survival of posterior cranial fossa and saddle nodule meningiomas is 6 years. The 10-year survival of meningiomas is 43% -78%. The main causes of death after surgery were failure to complete tumor resection, poor patient condition before surgery, tumor degeneration, or skull thickening. Factors affecting the prognosis of meningiomas are also various, such as tumor size, tumor histological characteristics, and degree of surgical resection. Patients with epilepsy after surgery are not only related to the tumor site, but also excessively pulling brain tissue during surgery, ligating or damaging the drainage vein.