What Is a Keratoma?

It is a congenital tumor that often occurs at the limbus and is mostly round and inferior to the outside. Substantial dermoid tumors are composed of fibrous tissue, covered with epithelial tissue, and hair follicles and sebaceous glands are sometimes seen. This suggests that fetal epithelial tissue can be resected by surgical relocation.

Corneal tumor

Corneal Tumor Dermatoid Tumor

It is a congenital tumor that often occurs at the limbus and is mostly round and inferior to the outside. Substantial dermoid tumors are composed of fibrous tissue, covered with epithelial tissue, and hair follicles and sebaceous glands are sometimes seen. This suggests that fetal epithelial tissue can be resected by surgical relocation.

Corneal Tumor Dermatoid Tumor Treatment

Carcinoma in situ

Also known as Bowen's disease. It is more common in the elderly, and it occurs at the junction of the cornea and conjunctiva. It is a gray-white translucent bulge. When there are more blood vessels, it is reddish. Pathologically, the cells show pleomorphic division, and the epithelium is poorly keratinized. However, the basement membrane of epithelial cells is still intact, and the lesions do not infiltrate into deep tissues. Can be completely removed.

"Ophthalmology" reports that topical use of interferon-2b is effective in treating recurrent corneal and conjunctival epithelial tumors.

Dr. Boehm MD and Dr. Huang AJW of the University of Minnesota point out that this topical treatment is beneficial and avoids the risks of surgery or other interventions, especially eye surface toxicity, changes in conjunctival plaque, and lack of limbal stem cells. This study looked at seven patients treated at the hospital from July 2000 to November 2003. Patients had surgery, radiotherapy, cryotherapy, or topical mitomycin C before relapse. It was found that 6 of these patients had reached Clinical Resolution. It takes an average of 14.5 weeks of interferon treatment to achieve clinical resolution, of which one patient achieved clinical resolution within 5 weeks. The mean follow-up time after the disease subsided was 11.7 months. Two of them had recurrence, one was 2 months after treatment and the other was 1 year after treatment. No treatment-related side effects occurred in all patients.

Based on this initial success, researchers hope to conduct large-scale controlled studies with longer follow-up to confirm the effectiveness and safety of local interferon treatment. [