What Is a Liver Biopsy?

Percutaneous liver puncture is based on the principle of negative pressure suction, and a rapid puncture method is used to extract a small amount of liver tissue from the liver. The tissue morphology changes are observed directly under the microscope, and clinical diagnosis is used to make a diagnosis of liver disease. However, due to the small size of the obtained specimen, it is still difficult to completely represent all liver lesions. However, like viral hepatitis, fatty liver, various types of cirrhosis, etc., the liver lesions are diffuse, so although the liver tissue removed is small, it can more accurately reflect the nature and extent of the lesion.

Liver biopsy

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Percutaneous

Percutaneous

What is the medical understanding of liver biopsy

Under ultrasound guidance

Liver biopsy is traumatic and sometimes difficult for patients to accept. It is mainly used for: the difference between focal fatty liver and tumors; in order to detect certain rare diseases, such as

Histological diagnosis of liver biopsy

The complete pathological evaluation includes three types of fatty liver, the site of hepatic acinar involvement, and the pathological classification and staging of fatty liver.

according to

(1) Blood pressure, pulse and chest x-ray should be measured before puncture, and emphysema, pleural hypertrophy, and blood type should be observed for blood transfusion if necessary. Diazepam 10mg can be taken 1 hour before surgery.

(2) The platelet count, bleeding time, clotting time, and prothrombin time should be checked before surgery. If there is any abnormality, vitamin Kllom9 should be injected intramuscularly once a day and rechecked after 3 days. For those who do not meet the puncture conditions for prothrombin time, 2 ~ 3u of fresh dry frozen plasma should be given before surgery; for those with low platelets, platelets should be transfused). >>>> Recommended reading: What are the examination items for hepatitis B patients

(3) Explain the purpose of puncturing to the patient and practice the breath-holding method (holding breath for a short time at deep exhalation). For those with cough, give codeine 0.039 1 hour before surgery.

(4) Preparation of supplies: sterile liver biopsy bag, high elastic abdominal band, disinfection gloves, 2% lidocaine, normal saline, specimen fixation solution, etc. The surgeon should be familiar with the operating procedures and carefully inspect the instruments.

(5) Ask for detailed medical history and medication. If anticoagulant is used, it should be discontinued at least 72 hours before puncture.

The results of liver biopsy pathological histology can provide a basis for diagnosis of various liver diseases or unexplained hepatosplenomegaly, help to determine, supplement or correct clinical diagnosis, help to discover liver fibrosis and early cirrhosis, and also help To judge the treatment effect and prognosis, understand the evolution of the disease. In addition, liver biopsy is also a treatment. Patients with liver abscess can extract pus through liver biopsy, and can also inject drugs through puncture needle. ^[1]