What Is Eosinophilic Folliculitis?

Eosinophilic pustular folliculitis is an inflammatory disease of unknown etiology. The disease is prevalent in men, and is mainly characterized by relapse, pruritus, clustering, follicular papules, and pustules in the seborrheic area, with a tendency to fuse. The disease is chronic, recurrent, and the duration and interval of the rash vary, which generally does not affect overall health.

Basic Information

Visiting department

Dermatology

Multiple groups

This disease is more common in men

Common locations

skin

Common causes

The cause of the disease is unknown

Common symptoms

The pimples are generally clustered, with a small amount of scales and pigmentation after the papules recede in the center, and new pimples on the edges, which gradually expand around.

Common symptoms

Expand to a certain extent and no longer increase, the realm is clear

Common symptoms

Pustules and pimples are often mixed

Common symptoms

Skin lesions can resolve on their own within weeks to months

Common symptoms

But can happen repeatedly in the affected area

Causes of eosinophilic pustular folliculitis

The etiology of this disease is unknown, and may be related to seborrhea and sex hormones; or a bacterial rash allergic to the hemolytic streptococcus antigen. Some people think that it is an allergic reaction to metals, such as gold, silver, tin, copper and so on.

Clinical manifestations of eosinophilic pustular folliculitis

The disease is more common in young men and young men, and clinically occurs in the face, chest and back, and proximal limbs. The pimples are generally clustered, with a small amount of scales and pigmentation after the papules recede in the center, and new pimples on the edges. They gradually expand to the surrounding area, and the lesions no longer increase to a certain extent. The realm is clear. Pustules and pimples are often mixed. Skin lesions can resolve on their own within weeks to months, but can occur repeatedly in the affected area. Aggravated skin lesions may be accompanied by systemic symptoms such as mild fever, diarrhea, and fatigue.
Most patients have acne or seborrheic dermatitis now or in the past, and some have a family history of asthma and eczema. The disease is chronic and recurrent, and generally does not affect health.

Eosinophilic pustular folliculitis examination

1. Blood tests Most patients have slightly increased peripheral blood leukocytes and eosinophils increased to varying degrees.
2. Pus culture is generally negative.
3. Pathological biopsy showed that an abscess formed in the hair follicle, which contained a large number of eosinophils and neutrophils.

Diagnosis of eosinophilic pustular folliculitis

The main points of diagnosis are as follows.
1. Typical Symptoms This disease occurs in young and middle-aged men. There are follicular papules, pustules, and mild itching in the area of seborrhea.
2. Auxiliary examination blood examination showed a slight increase in peripheral blood leukocytes and an increase in eosinophils; bacterial culture of pus was generally negative; pathological biopsy showed the formation of an abscess in the hair follicle with more eosinophils.

Differential diagnosis of eosinophilic pustular folliculitis

This disease needs to be distinguished from the following diseases.
1. Pustules The culture of pustules is positive. Histopathological examination shows that pustules and blisters are under the stratum corneum, and the pustules contain a large number of neutrophils. This disease is more common in young children and children. It often occurs in exposed areas. It is erythema, small blisters, and pustules in the early stage. After ulceration, it becomes a red erosion surface.
Microscopic examination and fungal culture of dandruff and dandruff were positive. The lesions are circular or multi-circular, with a central degeneration and clear edges, which are inflammatory pimples and papules. Itching is obvious, and it is mild or subside in summer and winter.
3. Histopathological examination of pustular psoriasis Kogoj pustules in the upper part of the spinous layer. It is often accompanied by high fever, joint swelling and pain, and general discomfort. The skin lesions are mainly flexion of the extremities and folds.

Eosinophilic pustular folliculitis treatment

Oral or topical glucocorticoids are effective, and some patients are effective with dapsone or sulfadiazine. A few patients improved after removal of tonsils, dental caries, or antibiotics.