What Is Nodular Prurigo?

Nodular prurigo is a chronic inflammatory skin disease characterized by sharp itching and nodular damage. The cause is related to insect bites, gastrointestinal disorders, endocrine and metabolic disorders, and neurological and mental factors. More common in women with this disease. Skin lesions are common in the extremities, and can also be found in the waist and hips, most often on the lower leg.

Basic Information

English name

nodularprurigo

Visiting department

dermatology

Multiple groups

female

Common locations

Calf extension

Common symptoms

Itchy, nodular damage

Causes of nodular prurigo

The cause of nodular prurigo has not yet been elucidated. Some patients develop the disease after being bitten by mosquitoes, bed bugs or other insects, and may be related to gastrointestinal disorders and endocrine disorders. Some people think that the disease is degeneration of localized chronic simple moss or atypical nodular localized chronic simple moss.

Clinical manifestations of nodular prurigo

The initial stage is a papule from the pin cap to the large rice grains, which gradually grows into a papule and nodules on the surface of the mung bean to large, hemispherical, solid bulge skin. , Scattered in isolation, touch a solid sense. As a result of severe scratching, exfoliation, bleeding, and hemorrhage occurred. The skin around the nodules is pigmented or thickened, showing a mossy appearance. Nodules are more common in the limbs, especially the lower leg extension, and occasionally in the back. The number varies, it can be as few as several or as many as dozens or more, and it is sometimes arranged in strips. Chronic process can last for a long time.

Nodular prurigo diagnosis

No special examination is needed to confirm the diagnosis, but it can be diagnosed based on verrucous nodular lesions, prevalent in the extremities, and severe itching. However, it needs to be distinguished from diseases such as verrucous lichen planus, papular urticaria, common warts, and primary skin amyloidosis.

Nodular Prurigo Treatment

General treatment

Improve sanitary conditions, prevent insect bites, remove related incentives, and avoid local irritation.

2. Common methods for nodular prurigo:

(1) Local treatment It can be used topically in various dosage forms of glucocorticoid or tar preparations, and can be externally applied with plasters containing triamcinolone acetate and neomycin. Local closed treatment: see injection of chronic simple moss for injection method.

(2) Systemic treatment The application of antihistamines and sedative sleeping pills is the same as that of chronic simple moss, and it can be used alone or in combination according to the severity of itching. Thalidomide has poor effect when used alone. Immunosuppressants, such as cyclosporine A and azathioprine, have a certain effect in the treatment of refractory nodular prurigo. Those who have obvious hyperplasia of skin lesions and those with hard texture can take orally retinoate, 3 times a day, or isotretinoin, 1 or 2 times a day.

(3) Physical therapy such as freezing, electrocautery, and laser therapy also have certain effects.