What Is Poorly Differentiated Adenocarcinoma?
Adenocarcinoma is a type of malignant epithelial tumor with adenoid structure or mucus secretion. It mainly occurs in the gastrointestinal tract, intrahepatic bile ducts, bile ducts (including the gallbladder), lungs, female reproductive tract and breast. Epithelial metaplasia, such as Barrett's esophagus and bladder with glandular cystitis. Malignant tumors are more or less differentiated into normal cells. The closer the tumor cell differentiation is to normal cells, the more mature it is. It is usually called well-differentiated, and some people call it grade . If the tumor cells are poorly differentiated and very immature, but still retain traces of some source tissue, it is called poorly differentiated, or grade III. The boundary between the two is called moderate differentiation, or grade II. Generally speaking, highly differentiated tumors have low malignancy and good prognosis, and poorly differentiated tumors have high malignancy and poor prognosis. Undifferentiated tumors have extremely high malignancy and have the worst prognosis.
Basic Information
- English name
- poor differentiated adenocarcinoma
- Visiting department
- Oncology
- Common locations
- Gastrointestinal tract, intrahepatic bile duct, bile duct (including gallbladder), lung, female reproductive tract and breast
- Contagious
- no
Clinical manifestations of poorly differentiated adenocarcinoma
- Different parts of poorly differentiated adenocarcinoma will have different clinical manifestations.
Diagnosis of poorly differentiated adenocarcinoma
- The diagnosis depends on histopathological or cytological diagnosis.
Treatment of poorly differentiated adenocarcinoma
- Surgical treatment can be taken according to the specific site, and radical resection or palliative resection of the lesion can be performed according to the different stages of the patient and the specific circumstances. In addition, according to the biological characteristics of the tumor and the overall situation of the patient, comprehensive treatment such as chemotherapy, radiotherapy, and immunotherapy is selected.