What Is the Connection Between Chlamydia and Mycoplasma?
Mycoplasma chlamydia is a creature widely existing in nature. It is not surprising that mycoplasma and chlamydia are found in the human body, and the human body's immunity is reduced, and they may all reproduce.
Mycoplasma chlamydia
- Mycoplasma chlamydia is a creature widely found in nature. Mycoplasma,
- Mycoplasma: 0.2 0.3um in diameter and relatively simple structure
- The pathogenic mechanism of chlamydia: can inhibit the metabolism of infected cells, lyse and destroy cells and cause the release of lytic enzymes, the cytotoxic effect of metabolites, causing allergic reactions and autoimmunity.
- Mycoplasma pathogenic mechanism: does not invade body tissues and blood, but after the respiratory or urogenital epithelial cells adhere and settle, it causes cell damage through different mechanisms, such as obtaining lipid and cholesterol on the cell membrane to cause membrane damage, Releases neurotoxins, phosphatases and hydrogen peroxide.
- Chlamydia immunity: When the body is infected with chlamydia, it produces specific immunity, but this immunity is weak and lasts a short time. Therefore,
- 1. In terms of cellular immunity, most active chlamydia patients who have been cured often cause delayed-type allergic reactions when given the corresponding antigen intradermally. This allergy can be passively transferred with lymphocytes. This immunity is likely to be mediated by T cells.
- 2. In terms of humoral immunity, it appears in serum and local secretions after Chlamydia infection.
- Well, if mycoplasma is found in the outpatient examination
- 1 Rapid antigen detection: Most monoclonal antibodies are used for direct immunofluorescence detection of chlamydia in samples. The 2I-IsA method can also be used to add anti-chlamydia antibody enzyme-labeled antibody 18G and substrate for quantitative and quantitative detection. These two methods are simple and sensitive.
- 2 blood routine: peripheral blood white blood cell count is generally normal eosinophilia.
- 3 PcR technology General PcR technology has the advantages of fast, convenient and specific detection of Chlamydia pneumoniae specific DNA. The sensitivity is higher than that of cell separation technology, but the effect is not ideal in the detection of throat swabs. Using nested PcR (nPcR) detection can significantly increase its sensitivity. .
- 4 x-ray examinations: Chlamydia pneumonia chest radiographs are non-specific, mostly unilateral inferior lobe infiltration, severe segmental pneumonia, and extensive bilateral pneumonia. Chlamydia trachomatis pneumonia chest radiographs show bilateral extensive interstitial and alveolar infiltration hyperinflation It is common to see large leaf consolidation.
- 5 Serological examination uses a complement binding test.The serum antibody titer in the recovery phase is 4 times or more than that in the acute phase.It is diagnostic but not early diagnostic.The micro-immunofluorescence method (MrF) is suitable for Chlamydia trachomatis.
- 6 Direct smear microscopy: take pharyngeal secretions, sputum, respiratory tract membranes or other specimens to make smears for GZmesa staining body stained with red starting body stained with dark blue chlamydia trachomatis inclusion body stained with brown due to glycogen 801 staining
- 7 Chlamydia isolation Chlamydia pneumoniae culture is best to use Hela cells or Hep-2 cells generally to take trachea or nasopharyngeal aspirate as clinical specimens for timely inoculation. Currently Chlamydia identification mostly uses Hela cells or Hep-2 cells to culture and pass specific monoclonal fluorescent antibodies Method (MFA) This technique is highly sensitive and specific. If the specimen can be collected early, a positive result can be obtained within 48 hours.
- Now, because "Mycoplasma chlamydia positive" is regarded as mycoplasma chlamydia infection, the treatment of "venereal disease" is "repeated", which is common in hospital clinics. So what exactly is Mycoplasma chlamydia? We know that the human body is not an absolutely sterile environment, only
- First of all, tetracycline, 500mg tetracycline 4 times a day for 7 days, or doxycycline 100mg 2 times a day for 7 days. For patients whose tetracycline is disabled or poorly tolerated, Jiaoyan Jieyin lotion containing PHMB bactericidal ingredients can be used twice a day for 7 consecutive days.
- In addition, newly developed
- Mycoplasma is mainly found in the luminal mucosa of humans and animals. Mycoplasma genital tract infection and
- The source of non-gonococcal urethritis is the patient, which is mainly transmitted through sexual relations. Like other sexually transmitted diseases, it occurs in the sexually active period of young people. One spouse is susceptible to the other, and pregnant women infected with chlamydia and mycoplasma are in the process of childbirth Can infect newborns.
- way for spreading:
- direct contact infection, and sexual intercourse with patients with non-gonococcal urethritis.
- Indirect contact infection, use clothes, bedding, towels, bathtub, toilet, etc. used by patients with non-gonococcal urethritis.
- Infection of the birth canal. Women with non-gonococcal urethritis infect the newborn through the birth canal. In addition, the fingers of the obstetrician and mother are also an important way to bring the pathogen to the newborn. With a complete fetal membrane, mycoplasma can be isolated from amniotic fluid, placenta, and fetal blood, thus proving that the fetus can also be infected in the uterus.