What Is the Connection Between Polydipsia and Diabetes?

Five years ago, Mrs. Rong's husband failed to compete for leadership positions. She held a wine bottle and wine as a companion every day. If she did not drink three or five glasses at each meal, she would feel uncomfortable. Whether at home or out, alcohol is indispensable every day, and most of them are high-grade liquor. Recently, he felt a little numb in his hands and feet. He went to the hospital for a checkup and had diabetes. The doctor said it was caused by drinking.

The greedy cup will only be closer to diabetes

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Five years ago, Mrs. Rong's husband failed to compete for leadership positions. She held a wine bottle and wine as a companion every day. If she did not drink three or five glasses at each meal, she would feel uncomfortable. Whether at home or out, alcohol is indispensable every day, and most of them are high-grade liquor. Recently, he felt a little numb in his hands and feet. He went to the hospital for a checkup and had diabetes. The doctor said it was caused by drinking.

China is a big country in alcohol consumption, and drinking has penetrated into every area of daily life. Similarly, the relationship between drinking and health, especially drinking and diabetes, has received increasing attention in recent years. Studies have shown that there is a close relationship between alcohol consumption and the onset of diabetes, that is, moderate drinking can reduce the incidence of diabetes, and conversely, excessive drinking can increase the incidence of diabetes. To this end, we remind friends who are happy and drunk every time they drink:

Excessive drinking is a comprehensive injury to the human body

Drinking affects people's health, and the effect is like a double-edged sword. In particular, excessive drinking causes multiple system and organ damage to the body, leading to alcoholic liver disease, including liver damage, fatty liver, cirrhosis, liver cancer, and major bleeding; causing indigestion, gastritis, gastric bleeding, alcoholicity Pancreatitis, pancreatic necrosis, etc. Alcohol also damages the nervous system, causing damage to the peripheral nervous system, causing peripheral neuritis, which is manifested as numbness of the limbs and weakness in walking; the central nervous system is mainly damaged by the brain, causing alcoholic encephalopathy, manifesting as memory loss, dementia.

Excessive drinking is a serious injury to the islets

Excessive drinking also increases the risk of diabetes, which is manifested in three main areas.

1. Affecting glucose metabolism: The liver is an important digestive organ of the human body and plays an important role in maintaining normal glucose concentration. When the concentration of glucose absorbed from the intestine into the blood increases, the liver stores its synthetic liver glycogen; when the blood glucose concentration decreases, the glycogen is decomposed to release glucose into the blood to maintain a stable blood glucose level. Some experimental studies have shown that alcohol (ethanol) and its metabolite acetaldehyde affect the glucose metabolism of the liver. Excessive drinking can cause glucose metabolism disorders and cause diabetes.

2. Islet injury: Excessive drinking will cause oxidative damage to the islets, cause islet cell apoptosis, and lead to islet damage. If the insulin secreted by the islets is absolutely or relatively lacking, it will cause the blood glucose concentration to rise, and a large amount of sugar will be excreted from the urine, and diabetes symptoms such as polydipsia, polyuria, polyphagia, weight loss, dizziness, and fatigue will appear. If you continue to drink a lot of alcohol, your condition will develop further, serious complications will occur, and your health will be threatened.

3. Signaling pathways that affect insulin's function: In order for insulin to function, it must also rely on specific signal pathways to transmit insulin signals into cells, thereby exerting insulin's metabolic regulation of nutrition. Excessive drinking can affect multiple links in this pathway, affecting the normal function of insulin.

Set a safe bottom line for drinking

The relationship between drinking and health has long been studied. Moderate drinking makes people feel euphoric, relax emotions, increase appetite, eliminate fatigue, promote sleep, and improve health. Many wines contain nutrients that can supplement the needs of the human body. Increasing evidence also shows that moderate alcohol consumption can reduce the incidence of diabetes. Long-term moderate alcohol intake has no deleterious effect on metabolism, but instead increases insulin sensitivity.

So, in the face of a wide range of wine, how to choose in daily life? How to grasp the scale of moderate drinking?

Generally speaking, wine is divided into liquor, beer and fruit wine. From a health perspective, red wine, which is one of the fruit wines, is preferred. There is a plant pigment component in red wine, which has the effects of anti-oxidation and anti-platelet aggregation. It can protect the elasticity of blood vessels, keep the blood flowing, and prevent the heart from ischemia. Drinking red wine often can reduce the risk of heart disease.

Except for a small amount of alcohol (ethanol) that is excreted through breathing and urine, more than 95% of the alcohol is catabolized in the body. The liver is an important organ for ethanol metabolism. The liver's daily metabolic capacity for alcohol is about 1 gram per kilogram of body weight. For a person weighing 60 kg, the amount of alcohol allowed per day should be limited to 60 grams. Those who weigh less than 60 kg should reduce their alcohol intake accordingly, and it is best to control it at about 45 grams.