How Do I Choose the Best Progesterone Capsules?

Progesterone capsules are indicated for threatened abortion and habitual abortion, premenstrual stress syndrome, anovulatory dysfunction and anovulatory amenorrhea, and combined use with estrogen to treat menopausal syndrome.

Drug Name: Progesterone capsule

Drug type: Prescription drugs, medicines for medical workers' injuries
Use classification: Progestins

Progesterone capsule ingredients

The main ingredient of this product is progesterone.
Chemical name: Pregn-4-en-3,20-dione.
Chemical Structure:

Molecular formula: C ₂₁ H ₃₀ O ₂
Molecular weight: 314.5

Properties of progesterone capsules

This product is a hard capsule with white or off-white powder.

Progesterone capsule indications

Threatened abortion and habitual abortion, premenstrual stress syndrome, anovulatory dysfunction and anovulatory amenorrhea, combined with estrogen for menopausal syndrome.

Progesterone capsule specifications

50mg.

Progesterone capsules dosage

Combined with estrogen (such as combined with estrogen, Premiere):
Premarin tablets: 1.25mg orally, once daily for 22 days; Premarin tablets from day 13 onwards, 200mg (4 capsules) twice daily for 10 days.
It is used for threatened abortion and habitual abortion, premenstrual tension syndrome, anovulatory dysfunction and anovulatory amenorrhea. The usual dosage is 200mg-300mg (4-6 capsules) daily, once or twice. Each dose should not exceed 200mg (4 capsules).

Progesterone capsule adverse reactions

Breakthrough bleeding, vaginal spotting, weight gain or loss, changes in cervical squamous junctions, changes in cervical secretion properties, breast swelling, nausea, and dizziness. Headache, burnout, fever, insomnia, allergies with or without pruritus, melasma, melasma, obstructive jaundice, abnormal liver function.

Progesterone capsules contraindicated

The following patients are disabled:
1. Those who are allergic to progesterone or other ingredients in this product;
2. Unexplained bleeding in the vagina;
3. Thrombophlebitis, vascular embolism, stroke or previous medical history;
4. Breast tumor or genital tumor.

Progesterone capsules precautions

1. Patients with kidney disease, heart edema and hypertension should be used with caution;
2. Once the clinical manifestations of thrombotic diseases (such as thrombophlebitis, cerebrovascular disease, pulmonary embolism, retinal thrombosis), the drug should be stopped immediately.
3. Sudden partial vision loss or sudden blindness, diplopia or migraine should be discontinued immediately.

Progesterone capsules for pregnant and lactating women

This product has not been found to have adverse effects on the fetus in animal experiments, but pregnant women may use this product only with the consent of a doctor. Progesterone is excreted in trace amounts in breast milk. So far no adverse effects on infants have been found. However, lactating women can use this product only with the consent of a doctor.

Progesterone capsules for children

Information is lacking.

Progesterone capsules for the elderly

Information is lacking.

Progesterone capsule drug interaction

Phenobarbital, phenytoin, rifampicin and other equal drugs can induce the cytochrome P450, which can weaken the efficacy of this product.
Ketoconazole is an inhibitor of cytochrome P450 enzymes. Therefore, ketoconazole or other cytochrome enzymes may increase the plasma concentration of progesterone.

Progesterone capsule overdose

Information is not available. If you take more than you should, consult your doctor.

Progesterone capsule pharmacology and toxicology

Progesterone is a steroid hormone secreted by the ovaries, placenta, and adrenals. In the presence of sufficient estrogen, progesterone can change the endometrium from the proliferative phase to the secretory phase, providing favorable conditions for implantation of pregnant eggs. After implantation of fertilized eggs, placenta is formed to support the excitability of the pregnant uterus and maintain Pregnancy status; can promote breast development and prepare for breastfeeding. This product can inhibit the release of luteinizing hormone from the anterior pituitary gland through negative feedback to the hypothalamus, prevent follicles from developing and mature, and inhibit the ovulation process of the ovary.

Progesterone capsule pharmacokinetics

After oral administration, it is metabolized in the liver, and about 12% is metabolized to pregnanediol, and the metabolite is combined with uronic acid and excreted with urine. After oral administration of 100 mg, the blood concentration reached a peak in 2-3 hours, and then gradually decreased, disappearing after about 72 hours, and the half-life was about 2.5 hours.

Progesterone capsule storage

Store in a shady, sealed, cool and dry place (not exceeding 20 ° C).

Progesterone capsule packaging

Packed in aluminum plastic, 10 tablets per plate, 2 plates per box.

Progesterone capsule expiration date

Tentative 24 months.

Progesterone Capsules

YBH20832004 ^[1]