Should I Take Caffeine and Acetaminophen Together?

Paracetamol / caffeine, the main component of this medicine, paracetamol, has analgesic effect by increasing the pain threshold, and has antipyretic effect by regulating the central temperature of hypothalamus. Because caffeine is a central stimulant, it can constrict blood vessels and reduce the amplitude of its pulsation, so it is compatible with antipyretic and analgesics to enhance the analgesic effect.