What Are the Best Treatments for Vitiligo In Children?

Children

patient

Vitiligo in children

Introduction to Vitiligo in Children

Children

patient

Because the body is in the development stage and the body's immunity is weak, in the process of treating vitiligo, attention should be paid to the toxic and side effects of the drug, and the medication should be used with caution and reasonableness to protect the physical and mental health and normal development of the child; Factors to avoid aggravating the condition;

Characteristics of Vitiligo in Children

Prevalence of Vitiligo in Children

The earliest onset of the disease occurs at birth, and it occurs before the age of 10, accounting for about 15% of the total number of patients with vitiligo. Women are significantly more than men.

Vitiligo- induced factors in children

The positive rate of family history of children is high, and the family often has a history of premature birth, indicating that genetic factors play an important role in the pathogenesis of vitiligo in children. , Suggesting that trauma may be a predisposing factor for vitiligo in children.

Children with Vitiligo

Vitiligo skin lesions in children

The distribution of skin lesions in children with vitiligo is about 50% in the head and neck, about 28% in both lower limbs, about 18% in the trunk, and about 6% in the perineum. The first place found is often external genitalia, Perianal and other places. The initial skin lesions are mostly in the vulnerable areas such as knees, elbows, forearms, hands, and heels.

Vitiligo skin lesions in children

Peripheral skin lesions in children account for 33% to 42% of the total number of children, 17% to 9% are distributed in the dermatome, and 30% to 50% are limited and circulated. Some materials show that about 41.3% of children with stage vitiligo are younger than 10 years old.

Changes in Vitiligo in Children

The age of skin lesions has little effect on the condition of vitiligo. Because children with vitiligo are mostly stable at this stage compared with adult patients, most children with segmental vitiligo can be relatively stable one year after the onset of disease.

Physical status of children with vitiligo

The number of children with autoimmune diseases is significantly less than that of patients with vitiligo in other age groups, but the detection rate of specific and non-specific autoantibodies is higher. For example, 152 children with vitiligo were tested for autoantibodies. 23 cases (15%) were positive for nuclear antibodies, 33 (22%) were positive for thyroid antibodies, and 23 (15%) were positive for thyroid microsomal antibodies, and among the children's first- and second-degree relatives, autoimmune The prevalence of the disease and the incidence of gray hair before development were higher than those of the normal control group. It is suggested that children with vitiligo have an increased risk of developing autoimmune diseases.

Vitiligo in children

Pediatric vitiligo mental state

Preschool children's main living environment is family, and often self-centered, vitiligo often does not cause psychological impact on children. However, children in school age are more sensitive to the neglect and mockery of the surrounding people. They have a stronger self-esteem and have been stressed, which leads to depression, loneliness, sleep disturbance, etc., and even inferiority, which can affect the stability of the disease and treatment effects.

Differential diagnosis of vitiligo in children

1. The diagnosis points of vitiligo in children include the phenomenon of deepening of the pigmentation of the skin with white spots, and some pigmentation bands.

2. The reliable method for the diagnosis of vitiligo in children is detection under a Wood lamp. The white spot of vitiligo under the Wood lamp shows pure white fluorescence, which is in sharp contrast with the surrounding normal skin, with clear boundaries and no scales.

3, the symptoms of vitiligo are acquired pigmentation spots or hypopigmentation spots, not congenital.

4, the white spots of vitiligo and the surrounding normal skin are clear, and the shape is irregular, the size is different, the development of vitiligo can be linked into a film at a later stage, the treatment is also more difficult, these are the main points of children with vitiligo symptoms.

It should be noted that the identification of vitiligo in children must be correctly distinguished from anemia moles. Vitiligo may occur in anyone, including children. The diagnosis of vitiligo in children is more difficult than in adults, because children have whiter skin and it is difficult to detect discoloration. At the same time, several types of pigmented nevus are common in children, with symptoms very similar to vitiligo, making identification difficult.

Anemia nevi is a loss of pigment that can occur after birth. It can occur in any part of the body. The skin lesions will gradually expand as the skin grows. It appears as single or multiple round or irregular light spots with irregular edges. clear.

As anemia nevi is a local vascular development abnormality, it is pressed with a slide glass during identification. There is no obvious boundary between the skin lesion area and the surrounding normal skin. If the palm is rubbed locally, the surrounding skin becomes red, and the skin lesion area is not red.

Treatment effect of vitiligo in children

Pediatric vitiligo is more sensitive to various recoloring therapies, and the rate of leukoplakia is higher than that of adults. However, as children are at the stage of physical and mental development, the adverse reactions of corticosteroids, immunosuppressants, oral PUVA and other therapies should be large. Physical development has different degrees of influence. Therefore, when formulating a treatment plan, the pros and cons should be weighed and treated on the premise of the best curative effect and the smallest side effects of drugs to maintain the normal physical and mental development of children.

Causes of Vitiligo in Children

Vitiligo foods and beverages for children

Small food drinks are sweet and delicious. Children can use them as snacks at any time, but they ca nt be time-based.

Regular meals disrupt the normal diet. Some small foods that do not meet the health standards will contain many chemical additives, such as colorants, preservatives, sweeteners, etc. will cause direct damage to children's bodies. Long-term partial eclipse leads to insufficient nutrient intake, and the decline in immunity due to malnutrition, which affects the normal development of the body and leads to the occurrence of many diseases.

Vitiligo industrial pollution in children

The causes of vitiligo in children also include: untreated exhaust gas, wastewater discharged from industrial production, and exhaust emissions from rapidly growing motor vehicles contain many substances harmful to the human body, such as sulfur dioxide, strong acids, strong alkalis, lead, arsenic, and mercury Chemical or heavy metal poisons such as benzene, phenol, etc. will directly damage the human body. All of the above factors are responsible for the increased incidence of skin diseases.

Vitiligo in children, agricultural pollution

Excessive use of chemicals in crops, such as pesticides, bactericides and ripening agents, etc. Meat and poultry residues in the body after being killed by excessive feeding of growth hormone will cause adverse effects on human health.

Treatment of Vitiligo in Children

The treatment of pediatric vitiligo should be treated differently from adults, and its effect is better than adults.

(1) Vitiligo in children has the following characteristics:

1. Age of onset: The shortest occurrence is 3 days after birth. The average age of onset is 4 to 5 years;

2. Girls are more common;

3. It is more common in segment type, followed by limitation type;

4. Eyes are easily affected;

5. The incidence of halo mole is as high as 8.5 percent;

6, easy to cause homomorphic reactions after trauma;

7, gastrointestinal dysfunction is obvious.

(B) the particularity of treatment of pediatric vitiligo-not suitable for pediatric use in conventional treatment:

1, systemic oral corticosteroids, there will be systemic or local side effects;

2. Whole body phototherapy is not suitable for children under 12 years old; local phototherapy is not suitable for children under 5 years old;

3. Surgical transplantation is difficult for children to cooperate and should not be used.

You can use:

1. Topical topical low-medium-effect corticosteroids; 2. Immunoenhancing agents; 3. Trace elements; 4. Oral Chinese patent medicine, the dose is halved; 5. Pure Chinese medicine

It is generally believed that the best time to treat patients with vitiligo in children is the stable stage, that is, the situation of white spot area no longer continuing to expand for 3-6 months.

Pure Chinese medicine treatment is also relatively safe for children with vitiligo. Compared to other ultraviolet irradiation and cell transplantation, pure Chinese medicine is the safest.

Precautions for the treatment of vitiligo in children

1. Early detection and early treatment: The shorter the onset of vitiligo, the easier it is to treat, so you must go to a regular hospital for treatment as soon as you find that your child has white spot symptoms.

2. Professional treatment: If you are sick, you can't go to the doctor. Don't believe in prescriptions, so as not to delay your illness, you should go to a regular hospital for professional treatment.

3. Symptomatic treatment and differentiated treatment: Decide how to use medicine according to the condition. In addition, because the physiological functions of children's nervous system and liver are not fully developed, it is necessary to consider both the needs of the disease and the adverse effects of the medicine on children's bodies when selecting drugs. factor.

Vitiligo in children

If your child has a cold and fever, don't take care and control the condition early, lest it develop into tonsil inflammation and increase the risk of vitiligo.

When the body's inflammation recurs and the life is irregular, the body mobilizes lymphocytes to resist the virus. This phenomenon of the body's spontaneous resistance to the virus is called "stress response". There is a "stress response" in the body, and most people have no problems. However, in the case of people with poor immune function, the "stress response" is still working after the inflammation is over, and there is a risk of vitiligo due to excessive effects.

Whenever there is inflammation in the body, such as colds, gastritis, pneumonia, tonsillitis, etc. At this time, the body's cells undergo a "stress response" to fight inflammation, which can easily induce vitiligo, and many children have a fever and fever, followed by tonsillitis. In particular, if the tonsillitis recurs, the stress system repeatedly acts, and vitiligo is more likely to occur.

Children with vitiligo pay attention to calcium

Vitiligo in children is likely to cause a large amount of calcium loss in the baby's body, and calcium is very important for the growth and development of the baby. The transmembrane flow of calcium and the concentration of intracellular and external cells have a great relationship with the pathogenesis of vitiligo. If the ion balance is abnormal, it will cause abnormal melanin production in the baby and cause vitiligo in the baby.

Vitiligo supplementation in children is usually chicken liver paste, which can be supplemented with phosphorus, a large amount of calcium, vitamin B2, zinc and protein, vitamin A, iron, vitamin B1, nicotinic acid and other nutrients. All infants over 6 months can Take. The raw materials are: 15 grams of chicken liver, 150 ml of chicken rack soup, a little of soy sauce and honey; when preparing, put the chicken liver in boiling water to remove blood water, cook for another 10 minutes, remove the outer skin and put it in a container for research Broken spare. Put chicken rack soup in a small pot, add the ground chicken liver, cook into a paste, add a little soy sauce and honey, stir well to serve;

Pediatric vitiligo diet attention

Vitiligo in children first, supplementary trace elements

Especially copper, iron, zinc. Studies have found that children with vitiligo are mostly related to the lack of trace elements. The lack of trace elements such as copper, iron, and zinc leads to insufficient tyrosinase activity in patients, damage to melanocytes, and reduced melanin synthesis.

Vitiligo in children second, do not be partial or anorexia

Most of the children with vitiligo have symptoms of low immunity, which has a lot to do with partial eclipse and anorexia. To improve immunity, the diet of children with vitiligo must ensure a balanced nutritional supplement. The healthy development of the human body requires various nutrients, especially when the child is in a critical period of physical development, and malnutrition should be avoided. Many children with vitiligo suffer from partial eclipse and anorexia, but parents often accompany their children, leading to a serious problem in the diet of many children with vitiligo.

Vitiligo in children third, eat less sweets and snacks

The nutritional value of sweets and snacks is not high, and polysaccharides have high heat energy. Long-term eating can cause malnutrition, induce diseases, and affect the normal development of children. Therefore, parents should limit or even prohibit their children's sweets and snacks. Never let sweets and snacks become Children's "staple food". Some studies have pointed out that if you eat sweets for a long time, your immunity will decrease and you will be vulnerable to diseases such as colds.

Vitiligo in children fourth, drink choice

Nowadays, various beverages have come out endlessly. Most of children's favorite beverages are mainly carbonated beverages, as well as coffee and other beverages. These beverages contain too much mineral phosphorus and caffeine, which will hinder the absorption of calcium and affect the height development of children. Therefore, fruit juice should be the main choice, it should be rich, and the mineral content is also good.

Prevention of Vitiligo in Children

Reasonable diet for children with vitiligo and strengthen nutrition

After illness, you should pay attention to adjusting your diet. Eat more high-protein, high-energy, and high-vitamin B-family foods, supplement a variety of trace elements, and eat more dark-colored foods, such as black beans, black rice, black sesame, and walnut kernels. , Black fungus, black date, mulberry, peanut and so on. Usually eat or not eat foods rich in vitamin C, such as tomatoes, oranges, grapefruit, apricots, hawthorn, strawberries, kiwi and so on. During the progress of the disease, it is necessary to avoid fatty products and fishy seafood. Parents should not agree to the children's requirements due to doting.

Diagnosis and treatment of vitiligo in children and strengthen nursing

After the illness, parents should send the child to the hospital for diagnosis and treatment, and assist the doctor to find possible predisposing factors. The treatment plan should be formulated and implemented under the guidance of the doctor. Intensive care to avoid trauma and infection, and actively treat other skin diseases associated with children. If the parents find that the child's condition is getting worse, they should be sent to the hospital for treatment in time to eliminate possible predisposing factors and adjust the treatment plan.

Proper use of vitiligo in children to avoid injury

There are many treatments for vitiligo, and some drugs and methods are not suitable for children, such as systemic application of immunosuppressive agents, antitumor drugs, and long-term, large-area topical corticosteroids. PUVA and surgical treatment with oral 8-MOP are not suitable for children. patient. The treatments with less side effects, such as ultraviolet radiation, immune modulators, traditional Chinese medicine and external medicines, can be selected, and the treatment plan should be adjusted in time to avoid iatrogenic injuries. Do not use sulfa drugs, cystine, penicillamine, vitamin C and other drugs that can aggravate the condition.

Combination of internal and external treatment of pediatric vitiligo

The concentration and dosage of external medicine for treating children with vitiligo should be appropriate to avoid irritation. When topical corticosteroids are used, medium and strong preparations should be selected. After the condition is controlled, the concentration and strength of the drug should be gradually reduced. It is not suitable for large-scale and long-term use. Avoid the use of irritating external drugs such as nitrogen mustard, calcipotriol, and camptothecin during the progress of the disease. In summer, you should also pay attention to the time and frequency of photosensitizing drugs on exposed areas, reduce the time of sunlight exposure, and prevent light. A toxic reaction occurs. And pay attention to the combination of internal therapy and treatment therapy to improve the efficacy.

Pediatric vitiligo continuous treatment to avoid intermittent

Various treatments for vitiligo require a long time to produce a curative effect. Do not take it too hurriedly during the treatment process, and you should stick to the medication patiently. Because children are difficult to accept and cooperate with complex treatment measures for vitiligo, especially topical therapy, it is difficult to adhere to peony every day, so relatives of children should be patiently guided, take proper care, insist on daily inspection and supervision of medication, and assist in the application of medication. And help children master the method of medication.

Psychological stress and mental injury in children with vitiligo

Vitiligo is an acquired depigmented skin disease. Psychological stress and mental damage can also affect the condition of children with vitiligo. Family discord, financial difficulties, poor living conditions, abuse, criticism, and rapport with classmates can all have an impact on the stability and treatment of vitiligo, and even rely on drugs to control the condition. They must bear the pressure of homework and the neglect of their classmates and the surrounding people. Therefore, while implementing bio-pigment therapy for children with vitiligo, they should integrate psychological treatment, give children comfort and care, reduce their psychological pressure and ideological burden, and avoid the outside world. The stimulation of adverse factors is also an important aspect in the treatment process. To create a relaxed living and learning environment for children, to make them have a happy and comfortable mood, and is conducive to the rehabilitation of patients.

Timely and effective treatment of pediatric vitiligo, combined with psychological treatment and good nursing measures, the condition can often be controlled and relieved, so that the area of skin lesions is reduced or even safely recolored, especially segmental vitiligo, which has a good prognosis and reasonable treatment. Will affect the normal development of children's physical and intellectual.

Pediatric vitiligo disease harm

The dangers of vitiligo

Vitiligo is the most frequently affected part of the face, arms and legs, which has a significant impact on the patient's appearance. This will cause huge psychological pressure on patients, which are all caused by vitiligo.

Harm of vitiligo 2. Endangering the health of patients

The harm of vitiligo to patients is also reflected in the health of patients, because vitiligo can cause many complications and threaten the health of patients. At the same time, these threats can bring psychological stress to patients and make them feel fearful.

Harm of vitiligo III. Treatment effect of severe harm to patients

Psychological factors are one of the factors that cause vitiligo, but also a major factor that affects the treatment of vitiligo. If you cannot maintain a good psychological state, it will bring great difficulty to the treatment of vitiligo. Poor spirit can easily lead to the disorder of immune function, and then hinder the production of melanin, which leads to vitiligo for a long time.