What Are the Common Imuran Side Effects?

Imuran is an important immunosuppressant for the treatment of SLE.

Imuran

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Imuran is an important immunosuppressant for the treatment of SLE.

In general, azathioprine has a stronger immunosuppressive effect than the above two drugs. It has been used in the past as an anti-rejection drug after organ transplantation, so it is more effective in controlling SLE activity. It has significant therapeutic effects on various manifestations of systemic lupus erythematosus, such as arthritis, pleurisy, vasculitis, and interstitial pneumonia. Especially for patients with lupus nephritis, the most significant application effect is to achieve clinical relief, consolidate curative effect, and reduce recurrence. Azathioprine can also be used as the first choice for patients who are not suitable for high-dose hormones, cyclophosphamide or other immunosuppressants. Due to its strong effect, side effects are also obvious. Some patients (about 1-3%) are allergic to the drug, and after a short period of time, symptoms of bone marrow suppression appear, showing white blood cells and / or thrombocytopenia, and the drug should be discontinued immediately; the vast majority of patients are not allergic to the drug and long-term The application is relatively secure. Take the dose: 50mg / tablet, 1 or 2 tablets a day. The key method for monitoring side effects is to review the peripheral blood cell count every 1-2 weeks after the initial medication. If the patient is not suitable for the drug, white blood cells and / or Platelet decline, which can be manifested within this time, early inspection is helpful to detect problems in time, stop the drug in time, and avoid further exacerbation of side effects. It is less likely that side effects of bone marrow suppression will occur after prolonged administration. Therefore, it is sufficient to review the peripheral blood signs regularly from January to February in the future. In the Shanghai market, azathioprine is available in both imported and domestic dosage forms. The dosage is the same. The imported one is three yuan; the domestic one is one yuan. The effect is similar, and the former may be less likely to cause side effects. Patients can choose according to their own financial situation.