What Are the Different Types of Prochlorperazine Tablets?
Chlorpromazine hydrochloride tablets, the indications are 1. It has a good curative effect on the positive symptoms such as excitatory agitation, delusional delusion, thinking disturbance and behavior disorder. For schizophrenia, mania or other psychotic disorders. 2. Stop vomiting, vomiting due to various reasons or stubborn hiccups.
Chlorpromazine tablets
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- Drug Name
- Chlorpromazine tablets
- Foreign name
- ChlorpromazineHydrochlorideTablets
- Whether prescription drugs
- Non-prescription drugs
- Athletes use with caution
- Inadvertent use
- Whether to include health insurance
- Not included
- Drug type
- tablet
- Character
- This product is a sugar-coated tablet
- Molecular formula
- (C17H19CLN2S.HCl)
- Chlorpromazine hydrochloride tablets, the indications are 1. It has a good curative effect on the positive symptoms such as excitatory agitation, delusional delusion, thinking disturbance and behavior disorder. For schizophrenia, mania or other psychotic disorders. 2. Stop vomiting, vomiting due to various reasons or stubborn hiccups.
- Basic Information
English name: ChlorpromazineHydrochlorideTablets
Page number: 2000 edition two-677
This product contains chlorpromazine hydrochloride (C17H19CLN2S.HCl) should be 93.0% to 107.0% of the labeled amount.
[Character] This product is a sugar-coated tablet, which is white after removing the sugar-coating.
[Identification] Take this product, remove the sugar coating, grind it, and weigh an appropriate amount of the fine powder (about 50mg of chlorpromazine hydrochloride)
Add 5ml of water, shake to dissolve chlorpromazine hydrochloride, and filter; the filtrate is tested according to the identification (1) and (3) under chlorpromazine hydrochloride,
Shows the same response.
[Check] The related substances are protected from light. Take an appropriate amount of this powder (equivalent to 0.1 g of chlorpromazine hydrochloride),
Add 10ml of methanol, shake to dissolve the chlorpromazine hydrochloride, filter, and take the filtrate as the test solution. According to the method under chlorpromazine hydrochloride, start from "precision amount and take appropriate amount", check according to law, and get it.
Dissolution operation is protected from light. Take this product, according to the dissolution test method (Appendix XC, the first method), take 1000ml of water as the solvent, the speed is 100 revolutions per minute, operate according to the law, after 30 minutes, take 10ml of the solution and filter, and take 5ml of the filtrate. Place in a 25ml volumetric flask, add hydrochloric acid solution (9 1000), dilute to the mark, shake well, and measure the absorbance at 254nm by spectrophotometry (Appendix IVA). According to the absorption coefficient of C17H19ClN2S.HCl (E1% 1cm )
The amount of dissolution per tablet was calculated for 915. The limit is 70% of the labeled amount, which should meet the requirements.
Others should comply with the relevant provisions under the tablet (Appendix IA).
[Content determination] Protect from light. Take 10 tablets of this product, after removing the sugar coating, accurately weigh, grind finely, accurately weigh an appropriate amount (approximately equivalent to 10 mg of chlorpromazine hydrochloride), put it in a 100 ml measuring bottle, add 70 ml of a hydrochloric acid solution (9 1000), and shake Dissolve chlorpromazine hydrochloride, dilute to the mark with the same solvent, shake well, filter, and accurately take 5ml of the filtrate, place it in another 100ml measuring flask, add the same solvent to the mark, shake well, and use spectrophotometry ( Appendix IVA). Measure the absorbance at a wavelength of 254nm. Calculate the absorption coefficient (E1% 1cm) of C17H19ClN2S.HCl as 915.
That's it.