What Are the Most Common Erythromycin Side Effects?

Produced by streptomycin Stretomyceserythreus, is an alkaline antibiotic. Its free base is for oral use and lactate is for injection. In addition, its ethyl succinate (erythromycin succinate) and dodecyl sulfate propionate (erythromycin) are also used for medicine.

Erythromycin injection

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1 The drug is unstable in acid and can be destroyed by gastric acid, so it is necessary to take acid suppressant at the same time

Erythromycin injection adverse reactions

Gastrointestinal reactions include diarrhea, nausea, vomiting, stomach cramps, pain in the tongue and mouth, and decreased gastric appetite. The incidence is related to the size of the dose. Allergic reactions are manifested as drug fever, rash, and eosinophilia, with an incidence rate of 0.5 to 1%. Use with caution in pregnant and lactating women.

Attention must be paid to: 1. Erythromycin is a bacteriostatic drug, and the administration should be performed at a certain interval to maintain the concentration of the drug in the body, which is conducive to the function. 2. Erythromycin tablets should be swallowed whole. If taking medicine powder, it will be destroyed by gastric acid and its effect will decrease. Toddlers can take acid stabilized erythromycin. Staphylococcus aureus is easily resistant to this drug. 3. Combined with -lactam drugs. It is generally believed that degrading effects can occur. 4. This medicine can obstruct the enterohepatic circulation of sex hormones, and it can reduce its effect when combined with oral contraceptives. 5. Erythromycin destroys and degrades in acidic infusion, and should not be compatible with low pH glucose infusion. In 500ml of 5% to 10% glucose infusion, add vitamin C injection (sodium ascorbate 1g) or 0.5ml of 5% sodium bicarbonate injection to raise the pH to about 6, then add erythromycin lactate, Helps stabilize.

Erythromycin injection side effects

1 gastrointestinal reaction, which may have nausea, vomiting, abdominal pain and diarrhea, the response is related to the size of the dose.

2 allergic reactions, there may be urticaria and drug fever.

3 can cause liver damage, such as increased serum alanine aminotransferase, jaundice and so on.

4 Intravenous injection or intravenous drip of erythromycin lactobionate can cause thrombophlebitis, intravenous injection is more likely to occur. Intramuscular injection is highly irritating and can cause pain and induration. Therefore, intramuscular injection is not recommended.