What Are the Uses of IV Cefazolin?

Cefazolin sodium for injection is a medicine

Cefazolin sodium for injection

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Cefazolin sodium for injection is a

Infective endocarditis, sepsis, arthritis, skin and soft tissue infections, urinary tract infections, pneumonia, bronchitis, otitis media, otolaryngology, respiratory medicine, nephrology, dermatology, orthopedics, infectious disease, cardiovascular medicine

Commonly used doses for adults: slow intravenous injection, intravenous drip or intramuscular injection, 0.5 to 1 g once, 2 to 4 times a day, severe infection can be increased to 6 g a day, divided into 2 to 4 intravenous administrations. Commonly used doses for children: 50 100mg / kg per day, 2 to 3 slow intravenous injections, intravenous drip or intramuscular injection. When the renal creatinine clearance rate is greater than 50ml / min, the renal function can still be normal.

The incidence of adverse reactions is low.

1 Thrombophlebitis and pain in the intramuscular injection area of intravenous injection are less and milder than ceftiophen.

2 The incidence of drug rash is 1.1%, and the incidence of eosinophilia is 1.7%, with occasional drug fever.

3 Individual patients may have transient elevated serum aminotransferase and alkaline phosphatase.

4 Patients with impaired renal function may experience encephalopathy when applying high doses (12g daily) of this product.

5 Occasional secondary infection of Candida albicans.

Those who are allergic to cephalosporins and those who have a history of anaphylactic shock or immediate reactions to penicillin are contraindicated.

1 Use with caution if you are allergic to penicillin or allergies. 2 Direct and indirect Coombs test positive and urine glucose false positive reactions (copper sulfate method) occur in about 1% of patients taking the drug.

1 This product is incompatible with the following drugs: amikacin sulfate, gentamicin, kanamycin, tobramycin, neomycin, chlortetracycline hydrochloride, tetracycline hydrochloride, oxytetracycline hydrochloride, myxomycetes Sodium mesylate, polymyxin B sulfate, erythromycin gluconate, erythromycin lactate, lincomycin, sulfaisoxazole, aminophylline, soluble barbiturates, calcium chloride, glucose Calcium heptanoate, diphenhydramine hydrochloride and other antihistamines, lidocaine, norepinephrine, m-hydroxylamine, methylphenidate, succinylcholine, etc. May also be contraindicated with the following drugs: penicillin, methicillin, hydrocortisone succinate, phenytoin sodium, prochlorperazine, vitamin B family and vitamin C, hydrolyzed protein.

2 Stability in sodium bicarbonate solution is worse than in other solutions.

3 This product should not be administered in the same container as aminoglycoside antibiotics. Precipitation can occur when mixed with vancomycin.

4 When this product is used in combination with strong diuretics such as aminoglycoside antibiotics or furosemide, renal function should be closely observed to avoid kidney damage.

This product has no specific antagonists. When the drug is overdose, it is mainly given symptomatic treatment and a lot of water and fluid.