What Factors Affect Combivent Dosage?
DDD refers to the average daily dose of a drug used by adults for primary therapeutic purposes.
DDD
(Limited daily dose)
Right!
- Chinese name
- DDD
- Foreign name
- Defined Daily Dose
- Types of
- Unit of frequency analysis
- Definition
- Average daily dose of adult drug for treatment purpose
- Features
- Not subject to treatment classification or dosage
- DDD refers to the average daily dose of a drug used by adults for primary therapeutic purposes.
- WHO developed anatomic-therapeutic-chemical drugs in 1969
- With DDD as the unit of measurement,
- Because the determination of DDD is the daily dose of drug evaluation for adults in order to achieve the main therapeutic purpose, due to the difference in drug dosage in the actual treatment process, the determination of DDD does not take into account the reduction in the dosage of patients with liver and kidney dysfunction, and there are also weight In the case of drugs, individual differences in drug use are not taken into account. Therefore, the drug consumption survey conducted by DDD can only show a rough consumption situation, not the exact and true frequency of medication. In addition, DDD is only a technical measurement unit used to compare different research results in drug utilization studies, not a practical dose recommended for clinical use. DDD values may vary in different countries or regions; DDD values only consider the main indications of the drug Dose of medication, which does not include the dosage of medication at different stages of the disease course, when the dose variation is large, or one drug can be used for more than one indication, or the non-compliance of first-class patients in combination medication, etc. The analysis should pay attention to its limits; DDD value is the daily dose for adults, and it will be low in children.
- DDD is a value based on adult medication, and children do not yet have a corresponding system; The main indication is in the drug ATC code. When the recommended dose needs to be calculated based on body weight, the body weight is set to 70 kg. It is emphasized that even preparations mainly used in children, such as mixed preparations and suppositories, are daily doses for adults. However, growth hormone and fluoride tablets are still based on the dosage used by children; DDD is usually established based on the maintenance dose of the drug, and some drugs with different initial doses cannot be reflected in DDD, such as digitalis; DDD is usually a therapeutic dose, but If the main indication is for prevention, choose the preventive dose. For example, DDD of fluoride tablets and some antimalarial drugs is the preventive dose; DDD usually does not give different salt preparations based on the pure product loading. DDD; DDD is expressed in terms of the weight of the pharmaceutically active substance. In determining the DDD of a drug, some special circumstances should also be considered. When different dosages are not used at the same time, different DDDs should be formulated. For compound preparations whose dose cannot be expressed by the weight of the active substance, the DDD is determined based on the number of unit doses, such as the number of tablets, capsules, or suppositories. DDD related concepts