What Is a Vitamin C Injection?
The concentration of this product is large, it is not suitable for direct bolus injection or intramuscular injection to avoid thrombus or hemolytic reaction.
- Vitamin C injection, 1. It is used for the prevention and treatment of scurvy, and it can also be used for auxiliary treatment of various acute and chronic infectious diseases and purpura. 2. Treatment of chronic iron poisoning: Vitamin C promotes the integration of deferoxamine to iron and accelerates iron excretion. 3. Treatment of idiopathic methemoglobinemia. 4. Patients with Keshan disease can be treated with large doses of this product when cardiogenic shock occurs. 5. Increased need for vitamin C in the following cases: (1) patients undergoing chronic hemodialysis, gastrointestinal diseases (long-term diarrhea, after gastric or ileal resection), AIDS, tuberculosis, cancer, ulcer, hyperthyroidism, Fever, infection, trauma, burns, post-surgery, etc .; (2) patients receiving parenteral nutrition due to strict control or diet choice, malnutrition, sudden weight loss, and during pregnancy and lactation; (3) application of Barbie Prototype, tetracycline, salicylic acid, or vitamin C as a urinary acidifier.
- Drug Name
- Vitamin C injection
- Hanyu Pinyin
- Wei Sheng Su C Zhu She Ye
- Drug type
- Work Injury Medical Insurance Class A Double Span
- Use classification
- Vitamin C supplements
Vitamin C injection warnings
- The concentration of this product is large, it is not suitable for direct bolus injection or intramuscular injection to avoid thrombus or hemolytic reaction.
Vitamin C injection ingredients
- The active ingredient of this product is vitamin C. The auxiliary materials are cysteine hydrochloride, sodium bisulfite or sodium metabisulfite, and disodium ethylenediamine tetraacetate.
Chemical name of active ingredient: L-ascorbic acid Chemical structural formula:
Molecular formula: C 6 H 8 O 6
Molecular weight: 176.13
Vitamin C injection properties
- This product is colorless to yellowish clear liquid.
Vitamin C injection indications
- 1. It is used for the prevention and treatment of scurvy, and can also be used for auxiliary treatment of various acute and chronic infectious diseases and purpura.
2. Treatment of chronic iron poisoning: Vitamin C promotes the integration of deferoxamine to iron and accelerates iron excretion.
3. Treatment of idiopathic methemoglobinemia.
4. Patients with Keshan disease can be treated with large doses of this product when cardiogenic shock occurs.
5. Increased demand for vitamin C in the following situations:
(1) The patient received chronic hemodialysis, gastrointestinal disease (long-term diarrhea, post-gastric or ileal resection), AIDS, tuberculosis, cancer, ulcer, hyperthyroidism, fever, infection, trauma, burn, post-operative, etc .;
(2) Patients receiving parenteral nutrition due to strict control or choice of diet, malnutrition, sudden weight loss, and during pregnancy and lactation;
(3) When using barbiturates, tetracyclines, salicylic acids, or vitamin C as a urinary acidifier.
Vitamin C injection specifications
- 2.5ml: 1g
Vitamin C injection dosage
- Intravenous injection, 0.5 ~ 1.0g (0.5 ~ 1), or as directed by your doctor. Immediately, it should be diluted with 5% or 10% glucose injection.
Keshan disease cardiogenic shock: the first dose of 5 to 10 g (5 to 10), slowly injected intravenously in 25% glucose injection.
Vitamin C injection adverse reactions
- 1. Long-term application of 2-3g daily can cause scurvy after discontinuation.
2. Long-term application of a large amount of vitamin C can cause urate, cysteine or oxalate stones.
3. Rapid intravenous injection can cause dizziness and syncope.
Vitamin C injection contraindications
- This product is combined with aminophylline, bleomycin, cefazolin, cefpirin, combined with estrogen, dextran, doxapram, erythromycin, methicillin, penicillin G, vitamin K, farwarin, heavy Sodium carbonate is contraindicated.
Vitamin C injection precautions
- 1. Vitamin C has not been proven to prevent or treat cancer, gingivitis, suppuration, bleeding, hematuria, retinal bleeding, depression, caries, anemia, acne, infertility, aging, arteriosclerosis, ulcer , Tuberculosis, dysentery, collagenous diseases, fractures, skin ulcers, hay fever, drug poisoning, vascular embolism, colds, etc.
2. Disturbance to diagnosis. Intensive use will affect the results of the following diagnostic tests:
(1) Occult blood in the stool can cause false positives;
(2) Can interfere with the results of automatic analysis of serum lactate dehydrogenase and serum aminotransferase concentrations;
(3) Urine sugar (copper sulfate method) and glucose (oxidase method) can cause false positives;
(4) Increased concentrations of sage boat, urate and cysteic acid;
(5) The serum bilirubin concentration rises;
(6) The urine pH decreases.
3. The following situations should be used with caution:
(1) Cysteineuria;
(2) gout;
(3) High oxalate urine disease;
(4) oxalate deposition disease;
(5) urate kidney stones;
(6) Diabetes (because vitamin C may interfere with blood glucose quantification);
(7) glucose-6-phosphate dehydrogenase deficiency (can cause hemolytic anemia);
(8) Hemochromatosis;
(9) Iron granulocyte anemia or thalassemia;
(10) Sickle anemia (can cause hemolytic crisis).
4. Sudden discontinuation of large-scale application for a long time may cause symptoms of scurvy, so it should be gradually reduced.
5. The concentration of this product is high, it is not suitable for direct bolus injection or intramuscular injection to avoid thrombus or hemolytic reaction.
Vitamin C injection for pregnant and lactating women
- This product can pass through the placenta. It can be secreted into milk. Large doses of pregnant women can cause infant scurvy.
Vitamin C injection for children
- This experiment was not performed and there are no reliable references.
Vitamin C injection for the elderly
- This experiment was not performed and there are no reliable references.
Vitamin C injection drug interactions
- 1. Large doses of vitamin C can interfere with the anticoagulant effect of anticoagulants.
2. Combined with barbitur or perimetone, it can promote the excretion of vitamin C.
3. Cellulose sodium phosphate can promote the metabolism of vitamin C to oxalate.
4. Long-term or large-scale application of vitamin C can interfere with the effect of disulfiram on ethanol.
5. Salicylic acid can increase excretion of vitamin C.
6. Should not be compatible with alkaline drugs (such as aminophylline, sodium bicarbonate, sodium glutamate, etc.), riboflavin, three gas tert-butanol, copper, iron (trace) solutions, so as not to affect the efficacy.
7. Compatible with vitamin K3, because the latter is oxidizing, which can produce redox reactions, making the curative effect of the two weaken or disappear.
Vitamin C injection overdose
- 1 ~ 4g daily, can cause diarrhea, rash, increased gastric acid, reflux of gastric juice, urinary stones, urinary oxalate and urate excretion, deep vein thrombosis, intravascular hemolysis or coagulation, etc. Sometimes it can lead to reduced phagocytosis of leukocytes. When the dosage exceeds 5g per day, it can cause hemolysis, which can be fatal in severe cases.
Vitamin C injection pharmacology and toxicology
- This product is a vitamin drug. Vitamin C is involved in the metabolism of amino acids, the synthesis of neurotransmitters, the synthesis of collagen and interstitial cells of the tissues, maintains the integrity of blood vessels, and promotes the absorption of non-heme iron; maintains immune function, increases resistance to infection; participates in detoxification functions, and It has the effect of antihistamine and prevents the generation of carcinogen (nitrosamine).
Vitamin C injection pharmacokinetics
- Low protein binding rate. Stored in small amounts in plasma and cells, the highest concentration is in glandular tissue. Intrahepatic metabolism, very small amounts are excreted by the kidney as the original or metabolites. When the plasma concentration is> 14ng / ml, the urine output increases. Can be cleared by hemodialysis.
Vitamin C injection storage
- Protected from light and sealed.
Vitamin C injection packaging
- Glass ampoules, 5 sticks / box; 10 sticks / box.
Vitamin C injection expiration date
- 18 months
Vitamin C injection standard
- "Chinese Pharmacopoeia" 2010 edition two