What Is Doxycycline Hyclate?

Doxycycline Hydrochloride (also known as doxycycline hydrochloride) is a light blue or yellow crystalline powder, odorless, bitter, hygroscopic, easily soluble in water and methanol, slightly soluble in ethanol and acetone . This product has a broad antibacterial spectrum and is effective against Gram-positive cocci and negative bacilli. The antibacterial effect is about 10 times stronger than that of tetracycline, and it is still effective against tetracycline-resistant bacteria. It is mainly used for respiratory infections, chronic bronchitis, pneumonia, and urinary system infections. It can also be used for macular rash, typhoid fever, and mycoplasma pneumonia. ^[1]

Doxycycline hydrochloride

Doxycycline Hydrochloride (also known as doxycycline hydrochloride) is a light blue or yellow crystalline powder, odorless, bitter, hygroscopic, easily soluble in water and methanol, slightly soluble in ethanol and acetone . This product has a broad antibacterial spectrum and is effective against Gram-positive cocci and negative bacilli. The antibacterial effect is about 10 times stronger than that of tetracycline, and it is still effective against tetracycline-resistant bacteria. It is mainly used for respiratory infections, chronic bronchitis, pneumonia, and urinary system infections. It can also be used for macular rash, typhoid fever, and mycoplasma pneumonia. ^[1]

[Alias]

[Pharmacological action] Antibacterial spectrum and tetracycline,

[Indications] Mainly used for upper respiratory tract infections caused by sensitive Gram-positive cocci and Gram-negative bacilli,

[Dosage and Administration] Oral: 0.1g once, twice a day. The first dose can be doubled if necessary. Children over 8 years old: the first dose is 4mg per kilogram of body weight; thereafter, 2mg per kilogram of body weight, twice a day. The general course of treatment is 3 to 7 days. Prevention of Plasmodium falciparum: 0.1g per week; Prevention of Leptospirosis: 0.1g twice a week.

[Precautions] 1. Gastrointestinal reactions are common (approximately 20%), such as nausea, vomiting, diarrhea, etc., can be reduced by taking medicine after meals. 2. For other adverse reactions, see tetracycline. 3. Usage should be twice a day, such as 0.1g once a day, it is not enough to maintain effective blood concentration. 4. In patients with mild liver and kidney dysfunction, the half-life of this drug is not significantly different from that in normal subjects, but those with severe liver and kidney dysfunction should be used with caution. 5. It should be generally banned for children under 8 years old, pregnant women and nursing women.