What Is Fenbendazole?
Fenbendazole is a white or off-white powder, which is odorless and tasteless. This product is soluble in dimethyl sulfoxide, slightly soluble in methanol, insoluble in water, and soluble in glacial acetic acid.
Fenbendazole
- Chinese name
- Fenbendazole
- Foreign name
- Fenbendazole
- EINECS number
- 256-145-7
- Molecular formula
- C15H13N3O2S
- Molecular weight
- 299.3476
- Fenbendazole is a white or off-white powder, which is odorless and tasteless. This product is soluble in dimethyl sulfoxide, slightly soluble in methanol, insoluble in water, and soluble in glacial acetic acid.
- Chinese alias: methylphenidamine
- English name fenbendazole
- English alias: methyl-5-phenyl-thio-2-benzimidazole carbamate; Phenthioimidazole; methyl N- (5-phenylsulfanyl-3H-benzoimidazol-2-yl) carbamate; methyl [6- (phenylsulfanyl) -1H-benzimidazol-2- yl] carbamate
- CAS number: 43210-67-9
- This product is off-white, crystalline powder. No smell. Tasteless. Melting point 233 ° C (decomposed). Insoluble in water, slightly soluble in organic solvents, easily soluble in dimethyl sulfoxide. Low toxicity. Oral LD50 in rats is above 10,000 mg / kg.
- Poultry has a good effect on the gastrointestinal and respiratory tract nematodes of poultry. 8mg / kg daily for 6 days, it is highly effective against chicken roundworm, capillary nematode and roundworm. The effective dose for turkey tapeworms is 350mg / kg at one time, but if fed continuously for 45 days at a feed concentration of 45mg / kg, all the turkey tapeworms, heterostomae and closed capillaries will be completely cleaned. The best insect repellent scheme for tadpoles, pheasants, grouse, geese and ducks is 60mg / kg feed concentration for 6 days. Naturally infected domestic pigeons with closed capillaries and pinworms, mixed feed at 100mg / kg for 3-4 days, the efficiency is almost 100%. [1]
- (1)
- Fenbendazole does not generally cause adverse reactions at conventional doses. As dead parasites release antigen, secondary allergic reactions can occur, especially at high doses. Vomiting is occasionally seen in dogs or cats.
- [note]
- (1) A single dose is often ineffective for dogs and cats and must be treated for 3 days.
- (2) Forbidden to feed horses.
- (3) Should not be used in dairy cows. It is also not used for the first 45 days of pregnancy.
- (4) Fenbendazole used in sheep and rabbits during early pregnancy may have teratogenic and embryotoxic effects.
- Shaded, sealed and stored in a dry place.
- Fenbendazole Tablets Fenbendazole Powder.
Fenbendazole Traditional Craft
- 4-Chloro-2-nitroaniline, thiophenol, sodium sulfide, and S-methylisothioureacarboxylic acid methyl ester are used as raw materials, and are obtained through condensation, reduction, and ring closure.
Fenbendazole two-step process
- The two-step process independently developed in China, also known as carbendazim process, uses 4-chloro-2-nitroaniline, thiophenol, hydrazine hydrate, and methyl cyanurate as raw materials, and is obtained by condensation, reduction, and ring closure. .