What Is Fexofenadine HCL?
The formulation of fexofenadine hydrochloride is mainly a tablet. It is a second-generation H1 receptor antagonist, which can selectively block the H1 receptor. It has a good antihistamine effect, but no anti-5 Serotonin, anticholinergic and antiadrenalin effects. Therefore there is no sedative effect and other central nervous system effects. Nor can it cross the blood-brain barrier. This product is suitable for the treatment of seasonal allergic rhinitis, chronic idiopathic urticaria and other diseases.
Fexofenadine hydrochloride
- The formulation of fexofenadine hydrochloride is mainly a tablet. It is a second-generation H1 receptor antagonist, which can selectively block the H1 receptor. It has a good antihistamine effect, but no anti-5 Serotonin, anticholinergic and antiadrenalin effects. Therefore there is no sedative effect and other central nervous system effects. Nor can it cross the blood-brain barrier. This product is suitable for seasonal
- [Ingredients] The main ingredient of this product is fexofenadine hydrochloride , and its chemical name is , -dimethyl-4- [1-hydroxy-4- [4- (hydroxydiphenylmethyl) -1-pipeline Pyridyl] -butyl] -phenylacetic acid hydrochloride.
- Chinese alias: Sonadine hydrochloride; alpha, alpha-dimethyl-4- [1-hydroxy-4- [4- (hydroxydiphenylmethyl) -1-pyridine] butyl] -phenylacetic acid Hydrochloride
- English name: Fexofenadine hydrochloride 2- [4- [1-Hydroxy-4- [4- (hydroxy-diphenyl-methyl) -1-piperidyl] -butyl] phenyl] -2-methyl-propanoic acid hydrochloride; Allegra
- Molecular formula: C32H39NO4 · HCL
- Molecular weight: 538.13
- Content: 98% -102%
- CAS Number: 153439-40-8 [1]
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- 1.Seasonal allergic rhinitis
- Fexofenadine hydrochloride tablets are used to alleviate the symptoms of seasonal allergic rhinitis in adults and children aged 6 years and over. These symptoms include sneezing, runny nose, itchy nose / stomach / throat, itchy eyes / Edema / redness.
- 2. Chronic idiopathic urticaria
- Fexofenadine hydrochloride tablets are suitable for treating skin symptoms of chronic idiopathic urticaria in adults and children aged 6 years and over, and can significantly reduce the number of itching and wind masses.
- [ Specification] 30mg
- 1.Seasonal allergic rhinitis
- The recommended dose of fexofenadine hydrochloride for adults, children 12 years of age and older is 60 mg twice daily, or 180 mg once daily. The recommended starting dose for patients with renal insufficiency is 60 mg once a day.
- For children 6 to 11 years old, the recommended dose of fexofenadine hydrochloride is 30 mg twice daily. The recommended starting dose for children with renal insufficiency is 30 mg once daily.
- 2. Chronic idiopathic urticaria
- The recommended dose of fexofenadine hydrochloride for adults, children 12 years of age and older is 60 mg twice daily. The recommended starting dose for patients with renal insufficiency is 60 mg once a day.
- For children 6 to 11 years old, the recommended dose of fexofenadine hydrochloride is 30 mg twice daily. The recommended starting dose for children with renal insufficiency is 30 mg once a day.
- Common adverse reactions were drowsiness, dry mouth, and drowsiness.
- The incidence of adverse reactions, including drowsiness, was not dose-related and was similar across age, gender, and ethnic groups.
- The literature reports that in a placebo-controlled trial of seasonal allergic rhinitis in the United States, the incidence of adverse reactions greater than 1% in patients over 12 years of age was as follows:
- Oral fexofenadine hydrochloride capsules twice daily had an adverse reaction rate greater than 1%.