What Is Guaifenesin?

Expectorant and antitussive, suitable for chronic bronchitis, bronchiectasis, etc.

Guaifenesin

Expectorant and antitussive, suitable for chronic bronchitis, bronchiectasis, etc.
Chinese name
Guaifenesin
Foreign name
guaifenesin guaiacol
Molecular weight
198.21
Molecular formula
C10H14O4
EINECS number
202-222-5
Drug Name: Guaifenesin
Drug aliases: meglyl ether; guaifenesin; guaiacol glyceryl ether; glycerol guaiacol
English name: guaifenesin; guaiacol
Chinese chemical name: 3- (2-methoxyphenoxy) propane-1,2-diol
English chemical name: 3- (2-Methoxyphenoxy) -1,2-propanediol
CAS RN .: 93-14-1
Physical and chemical properties: Melting point 77-81 ° C, boiling point 215 ° C (19 mmHg), water solubility 5 g / 100 mL (25 ° c)
Description: Tablets: 0.2g each, syrup: 1%, 2%.
Function: Stimulate the gastric mucosa after oral administration, and increase the bronchial secretion due to reflexivity, so that the sputum is diluted. With antiseptic and antiseptic effects, this product also has antitussive, antispasmodic and anticonvulsant effects. It is used for phlegm cough, lung abscess, bronchiectasis and secondary asthma in chronic bronchitis. Combined with other antitussive and antiasthmatic drugs. For cases where mucus is not easy to cough.
Dosage: Oral. Tablets, 0.1 to 0.2 grams for adults once, 3 to 4 times a day; children 15 mg once per kilogram of body weight, once every 6 hours. 10 to 15 ml of syrup at a time, 3 times a day.
Note: Nausea, dizziness, drowsiness and allergies. This product has the effect of stimulating and expanding vascular smooth muscle, so it is contraindicated in patients with pulmonary hemorrhage, acute gastroenteritis and nephritis.

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