What Is Lysine Hydrochloride?

Lysine hydrochloride is a white crystal or crystalline powder and is odorless. This product is easily soluble in water, very slightly soluble in ethanol, and almost insoluble in ether. Specific rotation is taken from this product, and it is precisely weighed. Add 6mol / L hydrochloric acid solution to dissolve and dilute to a solution containing 80mg per 1ml. According to law, specific rotation is + 20.0 ° to + 21.5 °.

Lysine hydrochloride

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Lysine hydrochloride is a white crystal or crystalline powder and is odorless. This product is easily soluble in water, very slightly soluble in ethanol, and almost insoluble in ether. Specific rotation is taken from this product, and it is precisely weighed. Add 6mol / L hydrochloric acid solution to dissolve and dilute to a solution containing 80mg per 1ml. According to law, specific rotation is + 20.0 ° to + 21.5 °.

Chinese name

Lysine hydrochloride

Character

White crystal or crystalline powder

Chinese name: Lysine hydrochloride

Chinese alias: L-lysine hydrochloride

English name: Lysine, hydrochloride

English alias: (2S) -2,6-Diaminohexanoic acid hydrochloride; (2S) -2,6-Diaminohexans? Urehydrochlorid; (L-lysinesalt); 233-234-9; DL-Lysine, monohydrochloride; L-Lysine chlorhydrate; L-Lysine hydrochloride (1: 1); L-Lysine, hydrochloride (1: 1); L-Lysinhydrochlorid ^[1]

Drug Name: Lysine Hydrochloride (Yansuan Lai'ansuan)

English / Latin name: Lysine Hydrochloride

Function Category: Vitamin OTC Drugs

Storage and shelf life: shading and sealed.

Category: amino acid drugs.

Identification: (1) The infrared absorption spectrum of this product should be consistent with the control spectrum (spectrum set 399). (2) Aqueous solution of this product

The acidity is 1.0g of this product. After adding 10ml of water to dissolve it, it is measured according to law (Appendix VI H). The pH value should be 5.0 6.0. The light transmittance of the solution is 0.5g. After adding 10ml of water to dissolve it, the light transmittance is measured at a wavelength of 430nm according to the spectrophotometry (Appendix IV A), and it must not be lower than 98.0%. Take 1.0g of sulphate and check it according to law (Appendix B). Compared with the control solution made of 2.0ml of standard potassium sulfate solution, it must not be more concentrated (0.02%). Take 0.10g of ammonium salt and check it according to law (Appendix K). Compared with the control solution made of 2.0ml of standard ammonium chloride solution, it must not be deeper (0.02%). For other amino acids, take this product, add water to make a solution containing 16mg per 1ml, as a test solution, accurately measure the appropriate amount of the above solution, add water to dilute to a solution containing 80g per 1ml, and use it as a control solution. According to the thin layer chromatography (Appendix V B) test, draw 5 l of each of the two solutions, point them on the same silica gel G thin plate, and use n-propanol-ammonia solution (2: 1) as the developing agent. Allow to dry, dry at 100 for 10 minutes, let cool, spray with ninhydrin acetone solution (1 50), dry at 80 for 5 minutes, and inspect immediately. The color of the impurity spots displayed by the test solution is in contrast to the control. The main spots of the solution must not be deeper (0.5%) compared. Take this product after losing weight and dry it at 105 for 3 hours. The weight loss should not exceed 0.4% (Appendix L). Ignition residues must not exceed 0.1% (Appendix N). Take 0.50g of iron salt and check it according to law (Appendix G). Compared with the control solution made of 1.5ml of standard iron solution, it must not be deeper (0.003%). Take 2.0g of this product, add 23ml of water to dissolve it, add 2ml of acetate buffer solution (pH3.5), and check according to law (Appendix H first method), the content of heavy metals must not exceed 10 parts per million. Take 2.0g of arsenic salt, add 23ml of water to dissolve, add 5ml of hydrochloric acid, check according to law (Appendix J first method), and it should meet the requirements (0.0001%). Pyrogen is taken, and sodium chloride injection is added to make a solution containing 22.5mg per 1ml, which is checked according to law (Appendix D). The dose is 10ml per 1kg of rabbit body weight, which should meet the requirements. The content of chlorine is about 0.35g of this product, and it is accurately weighed. After dissolving in 20ml of water, add 2ml of dilute acetic acid and 8-10 drops of bromophenol blue indicator solution, and titrate to silver-blue with silver nitrate titration solution (0.1mol / L). Each 1ml of silver nitrate titration solution (0.1mol / L) is equivalent to 3.545mg of Cl. Calculated based on the dry product, the chlorine content should be 19.0% to 19.6%.

Take about 80mg of this product, weigh it accurately, add 5ml of mercury acetate test solution and 25ml of glacial acetic acid, heat it at 60 70 to dissolve it, use potentiometric titration method (Appendix A), and use perchloric acid titration solution (0.1mol / L ) Titrate and correct the results of the titration with a blank test. Each 1ml of perchloric acid titration solution (0.1mol / L) is equivalent to 9.133mg of C6H14N2O2.HCl.

Lysine hydrochloride contained in this product is one of the essential amino acids in the human body. It is especially necessary for children during development, recovery from illness, and lactation. For example, lack of lysine can cause stunting, lack of appetite, weight loss, and hypoproteinemia.

oral. Adults, 300 mg each time. In children, 100 mg each time under 2 years old, 200 mg each time between 2 and 9 years old, and the same dose as an adult over 10 years old, both 1 or 2 times a day, dissolved in water, milk, milk cake or gruel.

1. Do not take when the properties of this product change.

2. Children must use under adult supervision.

3. Keep this medicine out of the reach of children.