What Is Mycophenolate Mofetil?

Oral absorption is rapid, with an average absorption rate of 94.1%. After a single oral dose, the plasma drug concentration reached a peak about 40 minutes to 1 hour, and the plasma protein binding rate was as high as 98%. Only a small amount of free MPA exerted its biological activity.

Mycophenolate mofetil

Oral absorption is rapid, with an average absorption rate of 94.1%. After a single oral dose, the plasma drug concentration reached a peak about 40min ~ 1h,

Mycophenolate mofetil (MMF) is

MMF is rapid in the body after oral administration

Prevent the same species

1.

The rejection dose should be taken within 72 hours of transplantation.

Compared with azathioprine and cyclosporin, the biggest advantage of MMF is that it has no obvious liver and kidney toxicity. Common adverse reactions are gastrointestinal reactions, manifested as nausea, vomiting, diarrhea, abdominal pain, etc., which can be reduced by adjusting the dose; anemia and

Patients who have an allergic reaction to MMF or MPA should not use this medicine.

Patients taking this medicine once a week during the first month

Medication for pregnant and lactating women

It was found in animal experiments

Cannot be with

Excessive MMF doses have not been reported in humans. Hemodialysis does not clear MPA, and when MPA plasma concentrations are very high (> 100 ug / mL), it can clear a small amount of MPAG. MPA can be cleared by increased drug excretion, such as cholestyramine administration.