What Is Pseudoephedrine Hydrochloride?
Pseudoephedrine hydrochloride, whose chemical name is [S- (R *, R *)]-a-1 [1- (methylamino) ethyl] -benzyl alcohol hydrochloride. It is suitable for reducing nasal congestion caused by colds, allergic rhinitis, rhinitis and sinusitis.
Pseudoephedrine hydrochloride
- Chinese name
- Pseudoephedrine hydrochloride
- Foreign name
- Pseudoephedrine Hydrochloride
- Pinyin name
- Yansuan Weimahuangjian
- product type
- Western medicine / Respiratory medicine
- Dosage
- Adult 0.12g (1 tablet) once a day, twice a day
- Functional indication
- Relieves colds, allergic rhinitis, rhinitis
- Pseudoephedrine hydrochloride, whose chemical name is [S- (R *, R *)]-a-1 [1- (methylamino) ethyl] -benzyl alcohol hydrochloride. It is suitable for reducing nasal congestion caused by colds, allergic rhinitis, rhinitis and sinusitis.
- Pseudoephedrine Hydrochloride
- This product is S- (R *, R *)-- [1- (methylamino) ethyl] -benzyl alcohol hydrochloride. Calculated on dry basis, containing C10H15NO.HCl should not be less than 99.0%.
- Western medicine / Respiratory medicine
- 0.12g
- The main ingredient of this product is pseudoephedrine hydrochloride, whose chemical name is [S- (R *, R *)]-a-1 [1- (methylamino) ethyl] -benzyl alcohol hydrochloride.
- oral. Adults 0.12g (1 tablet) once a day, twice a day.
- Indications: Reduce nasal congestion caused by colds, allergic rhinitis, rhinitis, and sinusitis, and control bronchial asthma.
- This product is white crystalline powder; odorless and bitter.
- This product is very soluble in water, easily soluble in ethanol, slightly soluble in chloroform.
- Melting point: The melting point of this product (Appendix VI C) is 183 to 186 ° C.
- Specific rotation is taken from this product, accurately weighed, dissolved with water and quantitatively diluted to make a solution containing about 50 mg per 1ml, and determined according to law (Appendix VI E). The specific rotation is + 61.0 ° to + 62.5 °.
- (1) Take this product, add water to make a solution containing 0.5mg per 1ml, and determine it by spectrophotometry. It has maximum absorption at 251nm, 257nm and 263nm wavelengths.
- (2) The infrared absorption spectrum of this product should be consistent with the control spectrum (spectrum set 642).
- (3) Identification of chlorides in aqueous solution of this product (Appendix III).
- Take 0.2g of this product, add 10ml of methyl red indicator solution after adding 10ml of water to dissolve, if it is light red, add 0.10ml of sodium hydroxide titration solution (0.02mol / L), the strain should be yellow; if it is yellow, add 0.10ml of hydrochloric acid titration solution (0.02mol / L), the strain turned red.
- Clarity and color of the solution take 1g of this product. After dissolving in 20ml of water, the solution should be clear, almost no opalescence and colorless; if it is cloudy, it should not be more concentrated than the turbidity standard solution (Appendix B).
- Loss on drying: Take this product and dry to constant weight at 105 . Lose weight should not exceed 0.5% (Appendix L).
- Ignition residues must not exceed 0.1% (Appendix N).
- Take 1.0g of heavy metal, dissolve in 23ml of water, add
- Take about 0.3g of this product and weigh it accurately. Add 10ml of glacial acetic acid, and dissolve slightly. Add 5ml of mercury acetate test solution and 1 drop of crystal violet indicator. Titrate with perchloric acid titration solution (0.1mol / L) until the solution becomes blue-green, and blank the titration result. Test correction. Each 1ml of perchloric acid titration solution (0.1mol / L) is equivalent to 20.17mg of C10H15NO.HCl.
- Protect from light and store in a sealed container.