What Is Sodium Phosphate?

Sodium phosphate is a phosphate and is an inorganic compound. It is prone to deliquescence and weathering in dry air, and generates sodium dihydrogen phosphate and sodium bicarbonate. Almost completely decomposed into disodium hydrogen phosphate and sodium hydroxide in water. Electroplating industry is used for the preparation of surface treatment degreasing liquid, alkaline detergent for unpolished parts. In synthetic detergent formulations, due to their high alkalinity, they are only used in strongly alkaline cleaner formulations, such as car cleaners, floor cleaners, and metal cleaners.

Chinese name: Sodium phosphate
Foreign name: trisodium phosphate anhydrous
Chemical formula: Na3PO4
Types of: Phosphate
Density: 1.62 (g / cm3)

Melting point: 340
Alias: Trisodium phosphate anhydrous
CAS number: 7601-54-9
EINECS: 231-509-8
PH value: 11.5-12.5

Physicochemical Properties of Sodium Phosphate

Sodium phosphate physical properties

Sodium phosphate is colorless or white crystal, contains 1 to 12 molecules of crystal water, and is odorless. When heated to 212 ° C or higher, it becomes anhydrous. Soluble in water (28.3g / 100mL), insoluble in ethanol and carbon disulfide. ^[1-2]

Sodium phosphate chemical properties

Its aqueous solution is strongly alkaline. ^[1]

It is heated to 55-65 ° C to form sodium phosphate decahydrate, heated to 60-100 ° C to form sodium phosphate hexahydrate, heated to 100 ° C or more to form sodium phosphate monohydrate, and heated to 212 ° C or more to form anhydrous sodium phosphate. It is prone to deliquescence and weathering in dry air, and generates sodium dihydrogen phosphate and sodium bicarbonate. Almost completely decomposed into disodium hydrogen phosphate and sodium hydroxide in water. ^[2]

Sodium phosphate toxicology data

The minimum lethal dose (rat, vein) is 1580 mg / kg. Groundhog LD ₅₀ by mouth: more than 2g / kg. ^[3]

Preparation method of sodium phosphate

Spray-drying method: Add trisodium phosphate dodecahydrate crystals to the dissolution tank, add 10% to 15% water, heat to 85-95 ° C, stir and dissolve, purify the solution, and pump the refined solution to the measuring tank. The atomizer is atomized, and the atomizer uses a two-flow air nozzle. The atomization steam guide angle and level are 30 °, the atomization steam pressure is 0.15 0.3Mpa, the inlet temperature is 650 750 , and the outlet temperature is 140 170 Spray-dried to obtain the finished product of anhydrous trisodium phosphate. ^[2]

Application field of sodium phosphate

Sodium Phosphate Medicine

Indications: True erythrocytosis, primary thrombocytosis, chronic myelogenous leukemia, chronic lymphocytic leukemia, and the identification of superficial masses. It is also used for neurodermatitis, chronic eczema, capillary tumors, keloids, pterygium Application of patellar meatus, corneal neovascularization, plasma cell tumor, etc.

Dosage: Erythrocytosis: Oral, 222MBq 296MBq (6mCi 8mCi) per course of treatment. Chronic leukemia: intravenous injection, each course of 148MBq ~ 185MBq (4mCi ~ 5mCi). Diagnosis of superficial mass: Oral, 7.4MBq ~ 11.1MBq (0.2mCi ~ 0.3mCi). After oral administration, the radioactivity was measured at the mass and corresponding side of the healthy side at 24h, 48h, and 72h, respectively. If the ratio is> 125%, the possibility of malignant lesions is greater. Dressing treatment: The dose depends on the type and extent of the lesion, and is usually administered in fractions.

Formulation specifications: solution (with carrier): 370MBq, 740MBq, 1850MBq, 3700MBq; injection (without carrier): 185MBq, 370MBq, 925MBq, 1850Mbq.

Note: Oral should be fasted. Before and after taking 32P, a low-phosphorus diet is required for one week, and phosphorus-containing drugs are banned. Repeat the treatment at least two months apart, and the dosage should be less than the first treatment. Patients under 20 years of age, pregnant women, lactating women, liver and kidney dysfunction, severe anemia, bleeding tendency and other patients are contraindicated.

Sodium phosphate food field

1. Work quality improver, which has the effect of increasing the complex metal ions, pH value and ionic strength of food, thereby improving the binding power and water holding capacity of food. China stipulates that it can be used for cheese with a maximum use amount of 5g / kg; the maximum use amount in western-style ham, meat, fish, shrimp and crab is 3.0g / kg; the maximum use amount in canned food, juice, beverages and dairy products is 0.5g / kg.

2. Used as analytical reagent and water softener, and also used for purification of sugar.

Sodium phosphate industry

Used as water softener and detergent, boiler antiscalant, fixing agent during printing and dyeing, mercerizing enhancer for fabric, metal corrosion inhibitor or rust inhibitor. Enamel industry is used as flux and decolorant. Used as hide degreaser and degumming agent in leather industry. ^[2]

Precautions for sodium phosphate

Sodium phosphate detection method

Analyze according to the analysis method specified in the chemical reagent product standard "HG / T 3493-2000" ^[4] Chemical reagent.

The sodium phosphate content (NA ₃ PO ₄ · 12H ₂ O) was sampled and dropped on the acidity meter to pH 8.8.

Determination of clarity: Take a sample and dissolve it in 10ML of water. Its turbidity should not be greater than the standard glass emulsion and the clarity standard HG / T3493-2000. It is calculated based on the determination of sodium phosphate.

Determination of chloride (Cl ^- meter): The turbidity of the sample should not be greater than the standard comparison solution.

Determination of phosphate (SO ₄ meter): measured according to the provisions of GB / T609, the yellow color of the solution must not be deeper than the standard comparison solution.

Determination of iron (based on Fe): The yellow color of the sample should not be deeper than the standard solution.

Sodium phosphate ecological data

This substance may be harmful to the environment. Special attention should be given to water bodies.

Sodium phosphate storage method

It should be stored in a cool, ventilated and dry warehouse, avoid moisture and avoid heat.

Sodium phosphate risk term

R34: Causes burns .. Causes burns. ^[5]

Sodium phosphate safety term

S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. After accidentally contacting the eyes, immediately rinse with plenty of water and seek medical advice.

S36 / 37/39: Wear suitable protective clothing, gloves and eye / face protection. Wear appropriate protective clothing, gloves and goggles or masks.

S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) If an accident or discomfort occurs, seek medical advice immediately (show the label if possible). ^[5]