What Is Sumatriptan Succinate?
Sumatriptan is also known as sumatriptan succinate. The chemical name is 3- [2- (dimethylamino) ethyl] -N-methylindole-5-methanesulfonamide succinate, and its molecular formula is C18H27N3O6S, molecular weight is 413.48800, density is 1.243g / cm3, melting point is 165-166 ° C, boiling point is 497.7ºC at 760 mmHg.
Sumatriptan
- Chinese name
- Sumatriptan
- Foreign name
- sumatriptansuccinate
- CAS number
- 103628-48-4
- Molecular formula
- C18H27N3O6S
- Molecular weight
- 413.48800
- Sumatriptan is also known as sumatriptan succinate. The chemical name is 3- [2- (dimethylamino) ethyl] -N-methylindole-5-methanesulfonamide succinate, and its molecular formula is C18H27N3O6S, molecular weight is 413.48800, density is 1.243g / cm3, melting point is 165-166 ° C, boiling point is 497.7ºC at 760 mmHg.
- Taking sumatriptan in large amounts can turn a person's blood green!
- Late one night in October 2005, a man was sent to St. Paul's Hospital for emergency surgery because of a "compartment syndrome" in his leg. The man was in a coma when he arrived at the hospital.
- The medical staff first inserted an arterial monitoring tube into the man's wrist artery before the operation officially started in order to monitor his vital signs such as blood pressure in real time during the operation. Under normal circumstances, the blood flowing out of normal people's arterial blood vessels is bright red. But in this case, something strange happened. Dr. Flicksman recalled: "Dark green blood was constantly flowing out of patients' blood vessels, instead of the bright red arterial blood under normal circumstances. No doubt we were stunned."
- The test report ruled out the possibility of methemoglobin.
- It turned out that the man took a long-term overdose of migraine drug sumatriptan, and the sulfur component of sumatriptan combined with hemoglobin made his blood eventually dark green.
- Sumaptan is a serotonin receptor agonist with high selectivity. It can shrink the intracranial arteries, redistribute blood flow, and adjust the cerebral blood flow supply. Trigeminal nerve activity is reduced, which relieves migraines. It also reduces neurogenic inflammation in the dura mater and helps treat migraines. [3]