What is transdermal estradiol?
transdermal estradiol systems are current adhesive patches containing estrogen. Healthcare providers commonly prescribe estradiol or estradiol as estrogen replacing after menopausal women and women experiencing conditions that inhibit the natural production of estrogen, can also use transdermal estradiol. The replacement of sex hormones was associated with an increased risk of developing certain cancers and cardiovascular disorders.
companies produce transdermal estradiol systems in various fixed pages of dose. Each patch usually contains five layers. The polyethylene pad includes the farthest layer. Another layer contains a reservoir of the drug. Under the drug lies a control layer that slowly releases sex hormone.
through the control layer of control release applies the adhesive. The overlapping polyester strips that the patient removes before applying the patch covers the adhesive. Women generally use the patch twice a week for cleaning, dry, unBroken and unprecedented skin. Common application points include lower abdomen, upper buttocks and external areas of the hip. Once the repair is held onto the skin, the user usually puts external pressure for approximately 10 seconds to activate the system.
Ovarian follicles contain the primary source of the estrogen body, hormone that regulates sexual development and maintenance and is responsible for the development of secondary sexual traits in women. Estrogen levels vary depending on the age and different phases of the menstrual cycle. The body usually transforms estrogen into estron and estriol, none of which has estradiol efficiency. Studies suggest that transdermal estradiol systems introduce hormone into the body more slowly and minimize conversion.
women who experience menopause often use transdermal systems of estradiol substitutes. Drugs generally facilitate vasomotor symptoms and osteoporosis often associated with the condition. Healthcare providers can alsoprescribe transdermal estradiol for women who experience ovarian failure or undergo ovarian removal. Women use medicines regardless of whether they keep their uterus.
Statistics generally suggest that when used separately, without progesterone, estradiol increases the risk of breast, endometrial or ovarian cancer. The hormone may increase the blood calcium levels in women with breast cancer or metastatic bones. Transdermal estradiol can also promote blood clots and increase the risk of heart attack, stroke or vascular embolism.
Other side effects associated with transdermal estradiol include elevated blood pressure and blood triglycerides. The hormone can also increase the likelihood of gall bladder disease. Nausea, headache and swelling are common side effects related to drugs. Women who replace thyroid glandulum simultaneously with estradiol may require modifications of their thyroid drugs.