What Is Tretinoin?
Retinoic acid is an intermediate product of vitamin A metabolism in the body, which mainly affects bone growth and promotes metabolic functions such as epithelial cell proliferation, differentiation, and keratinolysis. For the treatment of acne vulgaris, psoriasis, ichthyosis, lichen planus, pityriasis hair, follicular keratosis, squamous cell carcinoma and melanoma.
Retinoic acid
- Name: Vitamin A Acid, Retinoids
- Aliases:
- Orally, 10 mg / time, 2 to 3 times / day. For external use, 0.05% to 0.1% cream or ointment. For local application, 1-2 times / day.
- Pharmacology: Epidermal keratinocytes, melanocytes, and dermal fibroblasts are all important target cells for retinoic acid. Retinoic acid can affect
- 1 Can cause dry skin and mucous membranes, desquamation, nausea and vomiting, and loss of appetite.
- 2 Can cause headaches, dizziness, and pain in muscles and joints.
- 3 Teratogenic, pregnant women should avoid taking it.
- 4 Can cause liver damage, use with caution in patients with liver and kidney dysfunction.
- Retinoic acid, also called retinoic acid, is an important medicine for treating leukemia.
- CAS No .: 302-79-4
- Oral retinoic acid for experimental animals (including mice, rats, hamsters,
- ordinary
- For topical acne skin lesions, 0.1% ointment is applied topically and for acne skin lesions, 0.05% ointment is topically applied. Apply the medicine once every night after cleaning the skin with warm water, or as directed by your doctor.
- With medicinal soaps, cleansers, acne preparations, antidandruff preparations such as benzoyl peroxide,
- 1. Keep this product away from the eyes.
- 2. Should not be used on skin wrinkles.
- 3 Do not use other drugs, cosmetics or cleansers that can cause skin irritation and damage during the medication, so as not to aggravate skin reactions, increase drug absorption and cause systemic adverse reactions.
- 4 Sunlight can aggravate retinoic acid's irritation to the skin and lead to the breakdown of retinoic acid. Animal experiments suggest that retinoic acid can enhance the carcinogenic ability of ultraviolet rays. Therefore, this product is best applied at night and before bed. The sun should be avoided during treatment, or shading Measures.
- 5. This product should not be used in large areas, and the daily dosage should not exceed 20g.
- Women are disabled within the first 3 months of pregnancy. Acute or subacute dermatitis, eczema-like skin diseases are contraindicated.
- Although there is no evidence of teratogenicity caused by topical retinoids in human skin, but
- Topical application of this product may cause skin irritation symptoms such as burning sensation, erythema, and desquamation, which may make the skin lesions more obvious, but it also indicates that the drug is working, not aggravating the condition. Most of the skin can adapt and tolerate, and the irritation can gradually disappear. If the irritation persists or worsens, medication can be intermittently or temporarily suspended under the guidance of a physician.
- Retinoic acid