What Is Vilazodone?
Verazolone is a new type of antidepressant used in the treatment of adult major depression.
Verazodone
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- Chinese name
- Verazodone
- Foreign name
- vilazodone
- Types of
- New antidepressants
- approve the time
- January 21, 2011
- Verazolone is a new type of antidepressant used in the treatment of adult major depression.
- Vilazodone is a new type of antidepressant. It was approved by the US Food and Drug Administration (FDA) on January 21, 2011. It is produced by Trovis Pharmaceuticals LLC. The trade name of vilazodone is Viibryd. The approved vilazodone tablets are available in 10, 20, and 40 mg.
- The mechanism of vilazodone's antidepressant effect has not been fully understood. At present, it is believed that it is related to increasing serotoninergic activity by selectively inhibiting serotonin (5-HT) reuptake. Verazolone is also a 5-HT1A receptor Part of the agonist, but the results of 5-HT transmission and its antidepressant effect in vilazodone are currently unknown.
- The initial dose of vilazodone was 10 mg · d for 7 d, followed by 20 mg · d for 7 d, and then gradually increased to 40 mg · d. The recommended dose of vilazodone is 40 mg · d, which should be gradually reduced when the drug is discontinued. Do not stop the drug suddenly. Verazolidone should be taken with food. Fasting administration may lead to reduced drug concentration and reduced efficacy.
- Common adverse reactions (1%) of vilazodone include diarrhea, nausea, vomiting, and insomnia. Verazolidone does not cause changes in laboratory parameters, electrocardiogram (ECG), heart rate, blood pressure, and weight. Uncommon adverse reactions (1% to 1 ) include cataracts, paresthesia, metabolic and nutritional disorders, taste disorders, and frequent urination. , Panic attacks or mania.