What Are the Different Types of Fibromas?
According to the different age and location of the disease, it mainly includes juvenile fibromatosis, cervical fibromatosis, infantile fibromatosis, infantile fibromatosis, and lipofibromatosis. The age of onset is mostly 30 to 50 years old, and children and adolescents are not uncommon. Tumors can occur in large muscles in any part of the body. The rectus abdominis and the aponeurosis of adjacent muscles are the most common. They occur in pregnancy and late pregnancy. Those outside the abdominal wall are more common in men, and are more common in the scapula, thigh and hips.
Basic Information
- English name
- fibromatosis
- Visiting department
- Oncology
- Multiple groups
- 30 to 50 years old
- Common locations
- Rectus abdominis
- Contagious
- no
Causes of fibroma
- The cause is unknown, and some cases may be related to trauma or radiation exposure.
Clinical manifestations of fibromatosis
- According to the age of onset and the affected site, it is divided into:
- Juvenile fibromatosis
- Occurs in children and young people.
- 2. Cervical fibromatosis
- It is a fibroid disease that manifests at birth or shortly after birth and involves 1/3 of the sternocleidomastoid muscle, sometimes bilaterally. Cervical fibromatosis is often accompanied by various congenital abnormalities.
- 3. Infant finger (toe) fibromatosis
- It is a fibroid disease that is usually limited to childhood. The typical site is the outer side of the finger (toe), but it can also occur outside the finger (toe), such as the mouth and breast. The disease is often multiple and often develops at birth or within 2 years of age.
- 4. Myofibromatosis in infants and young children
- Single or multiple nodular lesions that occur in the skin, soft tissues, or bones can be confined to the above-mentioned areas or can be accompanied by internal organ involvement. The majority of this disease occurs before the age of two, and about 60% are congenital. The disease can also be seen in adults, with a single occurrence more common in males, and a more frequent occurrence in females. People with familial disease are known and evidence of autosomal dominant inheritance has been found.
- 5. Lipid fibromatosis
- It is a subtype of fibromatosis in infants and young children, and local recurrence is common.
- 6. Multiple hyalinizing fibromatosis
- It is a morphologically special, child-related, familial multiple fibroma disease that does not manifest at birth and may be caused by congenital metabolic abnormalities.
- 7. Other
- Penile fibromatosis, palm fibromatosis, plantar fibromatosis, scar fibromatosis, and post-irradiation fibromatosis. Fibroma disease with multiple colonic polyposis and occasionally multiple osteoma is called Gardner syndrome.
Fibroma test
- Histopathology: Morphology has characteristics between fibroblasts and smooth muscle cells. The proliferated cells have varying amounts of collagen, lack the characteristics of malignant cells, and have little or no mitotic figures, showing an invasive growth pattern. Lymphocyte infiltration can be seen around the blood vessels at the edge of the lesion.
Fibroma diagnosis
- Diagnosable by combining clinical manifestations and histopathology.
Fibromatosis treatment
- The treatment plan should choose timely and thorough surgical resection, which includes a wide area around the affected tissue, and sometimes it is necessary to remove the entire muscle involved. Only a few cases are forced to amputate because of local invasiveness. Radiation therapy may be effective for local control of the condition and is available after conservative surgery. Endocrine therapy has also been successful in some cases, such as tamoxifen. Recurrence rates are higher in young patients and large tumor volumes.