What Are the Symptoms of Candida Esophagitis?

Mycotic esophagitis should be combined with prevention and treatment. In particular, infections caused by iatrogenic factors should be prevented, and the indications for the use of antibiotics and hormones should be strictly controlled to reduce the incidence of the disease. There are many treatment methods, such as traditional Chinese medicines such as tin powder, Yunnan Baiyao, allicin, etc., western medicine nystatin, amphotericin B, ketoconazole, fluconazole, itraconazole and other antimycotic treatments are effective.

Mycotic esophagitis

Introduction to mycotic esophagitis

Mycotic esophagitis is mainly caused by Candida albicans infection. Candida is widely found in nature. It can be isolated from normal human skin, oral cavity, anus, and vagina, but the rate of bacteria in the digestive tract is the highest, accounting for about 50%. However, under normal circumstances, it does not cause esophagitis. When the body condition changes, such as the long-term use of broad-spectrum antibiotics; long-term treatment with hormones or anti-tumor drugs; chronic diseases and poor nutritional resistance caused by the host and microorganisms, etc. Disturbance between the dynamic balance and impaired immune function is prone to mycotic esophagitis. Mycotic esophagitis should be combined with prevention and treatment. In particular, infections caused by iatrogenic factors should be prevented, and the indications for the use of antibiotics and hormones should be strictly controlled to reduce the incidence of the disease. There are many treatment methods, such as traditional Chinese medicines such as tin powder, Yunnan Baiyao, allicin, etc., western medicine nystatin, amphotericin B, ketoconazole, fluconazole, itraconazole and other antimycotic treatments are effective.

Symptoms of fungal esophagus

Most patients with mycotic esophagitis come to the clinic for upper gastrointestinal symptoms, such as the feeling of swallowing foreign bodies, discomfort after sternum, acid nausea, and feeling of fullness. There may also be only epigastric discomfort and anorexia. During routine gastroscopy, doctors can find discontinuous dots and island-like white substances on the esophagus. Rinse with water is not easy to wash away. Perform a bacterial brushing smear and find fungal infections such as Candida albicans, Cryptococcus or Glomus

Causes of mycotic esophagitis

1. Long-term application of broad-spectrum antibiotics in large doses can inhibit sensitive bacteria in the body and disrupt the body's balance. For example, if certain Gram-negative bacilli that can produce antifungal substances are inhibited, the rate of mold reproduction will be accelerated.

2. Long-term application of a large number of adrenocortical hormones can promote lysis of neutrophils and macrophages, reduce antibodies, and increase the toxin effect of mold.

3. Large doses of radiation and the use of immunosuppressants cause the number of neutrophils and macrophages to decrease, and even directly damage normal tissues and cells, thereby creating conditions for mold infection.

4. Malnutrition, old age, wasting diseases, surgery, etc. will cause the body's cellular immune function to be low, and leukocyte phagocytosis and bactericidal functions to be reduced.

Mycotic esophagitis

Chronic diseases and long-term application of antibiotics can increase the chance of mold infection of the esophagus, leading to the occurrence of mold esophagitis. For example, patients with diabetes, chronic obstructive pulmonary disease, hematological disease, malignant tumor, chronic kidney disease, etc. However, it should be noted that some healthy people may also develop esophageal mold infections, which may be related to their temporary decline in immunity. In addition, Director Zhou Changjiang specially suggested that mycotic esophagitis often coexisted with oropharyngeal candidiasis or extremity fungal infection, and also suggested that healthy people may have secondary esophageal fungal infection. Treatment with antifungal drugs is usually required. Such as nystatin plus fluconazole for 24 weeks, individual patients need 6 weeks of treatment. Because patients with mycotic esophagitis are mostly patients with chronic diseases, symptoms of gastrointestinal reactions or liver and kidney damage may occur during long-term application. In order to avoid the side effects of antifungal drugs, once discovered by gastroscopy, a drug can be sprayed immediately. Through surface bactericidal action, fungal infections on the surface of the esophagus and mucosa can be effectively removed, and there are no side effects caused by antifungal drugs.