What Causes Elevated Creatinine Levels?

A higher creatinine than normal is called high creatinine. Creatinine includes blood creatinine and urine creatinine, but blood creatinine is more meaningful for measuring renal function. So high creatinine generally means high blood creatinine. In general, the normal value of serum creatinine is: 44-106 mol / L, but according to the current international new standard, it is 59-106 mol / L. When the blood creatinine exceeds 106 mol / L, it means that kidney may be damaged, renal insufficiency, Renal failure. (Above 106 mol / L is the period of inflammatory injury, 186 mol / L is the period of renal impairment, and 451 mol / L is the period of renal failure). Creatinine in the body is mainly produced by the muscles and excreted by the kidneys. In general, the amount of creatinine produced is constant, and the level of blood creatinine depends mainly on how much creatinine is excreted by the kidneys. The kidney's compensation function is very powerful. If both kidneys are normal, as long as one kidney is functioning, blood creatinine can be maintained at normal levels. That is to say, renal function must be reduced to half the normal level before it can cause blood creatinine to rise. Therefore, serum creatinine does not fully reflect the cause of early, mild renal decline.

High creatinine

1. Dehydration in the body, such as fever, sweating, and reduced drinking water, polyuria leads to blood concentration, decreased renal blood flow, and increased creatinine.

2. Excessive fatigue, poor rest, and inattention to details of life can also cause a certain range of elevated serum creatinine.

3. People with abnormal urine and long-term hematuria and proteinuria will unknowingly increase creatinine.

4. Patients with kidney disease have taken kidney-damaging drugs under unknown circumstances, and they may have increased creatinine, or even irreversible.

5. People with renal insufficiency will experience a rise in creatinine in the short term when they are infected (including colds, pneumonia, intestinal infections, urinary tract infections, etc.).

6, Hypertension patients, blood pressure is unstable, will appear

1, water metabolism disorders: including polyuria, increased nocturia, thirst, dry mucous membranes, fatigue, etc .; or systemic edema, increased blood pressure, pulmonary edema, and heart failure.

2, sodium metabolism disorders: high creatinine will also appear hyponatremia or hypernatremia.

3, potassium metabolism disorders: high creatinine is often accompanied by hyperkalemia or hypokalemia.

4.

In addition to adhering to the principle of being good for your health without increasing the burden on your kidneys, you should also pay attention to some details. Specifically, a diet high in creatinine is as follows:

Limitation of salt: Generally speaking, patients with renal insufficiency and azotemia stage have high blood creatinine and begin to show various mild clinical symptoms. However, due to moderate pathological damage, hypertension and edema can be seen. Situation, control salt intake, give low-salt or salt-free diet, respectively.

Protein supply: Because patients with azotemia in this period,

1, sodium metabolism disorders: high blood creatinine will also appear hyponatremia or hypernatremia.

2. Abnormal metabolism of aluminum, magnesium, copper, zinc, and selenium.

3. Metabolic acidosis: Patients with high blood creatinine have deep and long breathing, lack of appetite, abdominal pain and nausea, vomiting, weakness, headache, restlessness and even coma.

4, water metabolism disorders: polyuria, increased nocturia, thirst, dry mucous membranes, fatigue, etc .; or systemic edema, increased blood pressure, pulmonary edema and heart failure and other symptoms.

5, potassium metabolism disorders: high serum creatinine is often accompanied by hyperkalemia or hypokalemia.

Dialysis therapy: It is the discharge of toxic substances from the patient's blood. In other words, the patient

Serum creatinine and creatinine clearance are not completely consistent, and creatinine clearance is more sensitive than blood creatinine. In the early stages of renal insufficiency (compensation phase), creatinine clearance decreases while blood creatinine is normal. When the glomerular filtration rate drops to more than 50% of normal, blood creatinine begins to increase rapidly, so when the blood creatinine is significantly higher than normal, it often means that renal function has been seriously damaged. Because creatinine clearance is also affected by glomerular concentrating function, in the case of impaired renal concentrating function, blood creatinine is the most reliable indicator of glomerular function. Normal male blood creatinine is 53-106 mol / L, female is 44.2-97.2 mol / L.

After the increase in serum creatinine, the most important thing is to take treatment measures. Although there may not be a high increase in serum creatinine, the renal damage is already serious because the kidney has a strong compensatory function. In light and moderate injuries, the serum creatinine increases It may not be obvious. Generally, when the renal function damage is more than 80%, the serum creatinine is significantly increased. Therefore, once an increase in serum creatinine is found, it should be treated early.

When patients with elevated creatinine should first pay attention not to use drugs that induce renal damage, such as painkillers. Second, visit the hospital regularly to observe the changes in creatinine and urea nitrogen. Again, don't be tired or stay up late in your life, take appropriate exercise and be prepared to prevent infection. The last is a scientific and reasonable diet, which is based on a light diet. Do not eat greasy foods. Foods that contain high purines cannot be eaten. You can eat foods that contain high-quality protein but not in large quantities.

When creatinine rises, patients will have symptoms, but they are just ignored. When people's creatinine value is height, symptoms such as increased nocturia, fatigue, thirst, edema, increased blood pressure, heart failure, pulmonary edema, etc., are manifestations of imbalanced water metabolism. When metabolic acidosis occurs, patients do not want to eat, weakness, restlessness, abdominal pain, vomiting and even coma. These are relatively obvious symptoms. In addition, patients with elevated creatinine will also find that they have hyponatremia, hypokalemia, slow growth, sexual dysfunction, etc. These are also a manifestation of high creatinine. When people have the above symptoms, they should go to the hospital for a detailed physical examination. Do not ignore that it is caused by fatigue.

1. Ensure sufficient water for human body. Only by ensuring a sufficient amount of water, drinking more water can make creatinine and some waste poisons go out of the body through the kidneys and urine.

2. Increase your immunity. If the body's immunity is good, it will not only help prevent the occurrence of high creatinine, but also prevent other diseases to harm the human body. Physical fitness can be enhanced through proper physical exercise.

3. Limit the amount of salt in your diet. In order to reduce the occurrence of edema caused by excessive intake of salt, too much salt will also increase the burden on the kidneys, leading to metabolic disorders in the human body, and the creatinine value will increase accordingly.

4. Also pay attention to low protein diet. Can eat some good protein foods, such as meat, eggs, milk, etc.