What Causes Itching All Over?

Substances that cause allergic reactions are called allergens, such as pollen, house dust, fish, shrimp, milk, eggs, penicillin, sulfa, quinine and so on. When some people are exposed to allergens, they are stimulated by allergens to produce antibodies from effector B cells. Some antibodies are adsorbed on the skin, respiratory or digestive tract mucosa, and on the surface of certain cells in the blood. When the same allergen enters the body again, it will bind with the corresponding antibody adsorbed on the cell surface, causing the cells to release substances such as histamine, causing capillary dilation, enhanced blood vessel wall permeability, smooth muscle contraction, and glandular secretion. Increase and so on.

Allergic reaction

An allergic reaction is a reaction that occurs when an immune body is stimulated by the same substance again. The response is characterized by rapid onset, strong response, and rapid regression; generally it will not damage tissue cells, nor cause tissue damage. Obvious genetic predisposition and individual differences. Systemic allergic reactions refer to allergic symptoms in more than two organs. It is a more severe allergic reaction.

Affected area

whole body

Related diseases

Anaphylactic shock asthma allergic asthma skin allergy medication allergy fungus allergy food allergic asthma pollen allergic asthma allergic bronchopulmonary aspergillosis ant bite

Related symptoms

Pimples systemic allergic reaction systemic allergy and fever rash joint pain blister shock drug allergic reaction

Affiliated Department

Rheumatology and Immunology

Related inspections

Antigen intradermal test

Substances that cause allergic reactions are called allergens, such as pollen, house dust, fish, shrimp, milk, eggs, penicillin, sulfa, quinine and so on. When some people are exposed to allergens, they are stimulated by allergens to produce antibodies from effector B cells. Some antibodies are adsorbed on the skin, respiratory or digestive tract mucosa, and on the surface of certain cells in the blood. When the same allergen enters the body again, it will bind with the corresponding antibody adsorbed on the cell surface, causing the cells to release substances such as histamine, causing capillary dilation, enhanced blood vessel wall permeability, smooth muscle contraction, and glandular secretion. Increase and so on.

Allergen

Damaged skin structure

2. Decreased skin immune and protective function.

Allergy

1. Meet the wind, meet the cold, meet the heat, meet the hot, meet the sun, meet the excitement, meet the hands, meet the oppression, meet the seafood, meet the cosmetics, meet the bite, meet the dust, meet the pollen, meet the cold water

2. Various fake and shoddy cosmetics or cosmetics that are not suitable for you

3. After peeling Chinese herbs or chemicals

4. Long-term application of hormone-containing ointments or cosmetics

5. Damage the skin after healing of oily skin or acne.

6. Age: Perhaps increasing age is an important cause of skin sensitivity. Some people's skin was not sensitive in previous years, but in recent years they have become sensitive. This is because there is a weakly acidic sebum film on the surface of young and healthy skin, which retains moisture to protect the skin from external aggression, but with age, this layer of sebum film is not as healthy as before, even some sensitive substances Easy to invade skin.

7. Pets: Sensitive skin is prone to allergies due to the fur of domestic pets. The cause of allergies due to pets is mainly due to the proteins secreted by the oil glands of cats and dogs. When pets lick their hair, these proteins stick to the fur, and then they are scattered in the air and attached to people. Caused on the skin.

8. Seasonal change: Due to various environmental factors, allergens such as bacterial spores and pollen scattered in the air will release a large amount of compounds mdash; mdash; histamine, which causes facial skin irritation, which spreads almost all human tissues.

9. Temperature change: The temperature is suddenly cold and hot, making the face of sensitive people red and hot.

10. Ultraviolet rays: Ultraviolet rays cause facial skin irritation.

The main symptoms are swelling of the extremities of the whole body, redness throughout the body, small pimples, long blisters, and itching all over the body.

Spotting allergens

The prick test can be regarded as a special intradermal test, and it is currently the internationally-especially tested method for allergens in Europe and the United States. Because it is the skin puncture solution which is only one ten thousandth of the intradermal test, it has high safety and sensitivity, and high accuracy. Because the skin lesion is small, the patient is painless. It is gradually replaced by mosquito bites The traditional intradermal test.

principle:

When certain allergens enter the skin, patients who have an allergic reaction to certain substances immediately and specifically cause degranulation of mast cells in the skin and release active substances such as histamine, resulting in local capillary dilatation (erythema) ), Capillary permeability is enhanced (edema, wind mass), and those who are positive indicate that they are allergic to the antigen.

Total IgE test

Total IgE test is a detection method to determine the body's allergic constitution, and it is an important sign of allergy. When it increased, there was no parasitic infection, indicating that the patient was in an allergic state.

Food intolerance

Clinically proven that many chronic diseases are related to food. After removing the problematic food, the symptoms will disappear. This is food intolerance. Food intolerance testing is also the only late-response (IgG) test for food allergies. Diarrhea, oral ulcers, urticaria, acne, migraine, fatigue, depression, asthma, sleep disturbances, molars and other chronic symptoms. If the cause cannot be found, food intolerance testing should be done, all may be food intolerance related.

UniCAP detection

The UniCAP fully automated in vitro diagnostic system developed by the Swedish Famacia company is currently the most advanced allergen laboratory system in the world and has been confirmed by the International Committee of Clinical Laboratory Standards. With its high safety and accurate and reliable test results, it has been confirmed by the World Health Organization, and has been internationally hailed as the gold standard for allergen detection. Principle: Allergens are covalently bound to CAP's cellulose solid-phase support and react with specific IgE antibodies in patient serum samples. Based on the World Health Organization (WHO) IGE reference, a standard curve is drawn, and the IgE concentration in the sample can be calculated from the fluorescence intensity. Detection types: can detect more than 600 allergens including inhalation and food. Through simple blood sample collection, the test results can be obtained quickly and accurately, and the degree of allergy can be detected at the same time. Because the test is accurate and can quantitatively measure the degree of allergy, it greatly reduces human errors, guarantees the credibility of the test results, and provides a reliable basis for clinical treatment of doctors.

Differential diagnosis of systemic allergic reactions:

1. Systemic allergy and fever rash arthralgia: Acute allergic triad is a clinical manifestation of interstitial nephritis caused by acute drugs. That is, the patient has a systemic allergic reaction and fever, rash, and joint pain.

2. Drug allergic reactions: Drug allergic reactions refer to the adverse reactions of patients with specific constitutions after using certain drugs. It has nothing to do with the dose of the drug. The incidence of drug allergic reactions is not high. There are two main forms: one occurs at the time of medication, called an immediate reaction; the other is a latency reaction that occurs after half an hour or even a few days, and is called a late response. It manifests itself as rash, asthma, and fever; in shock, it can be life-threatening. The main symptoms are swelling of the extremities of the whole body, redness throughout the body, small pimples, long blisters, and itching all over the body.

As the allergic reaction is caused by the body's contact with the allergen, finding out the allergen and avoiding contact with the allergen as much as possible is the main measure to prevent the occurrence of allergic reaction. If you cannot find the allergen yourself, it can be detected by your doctor using medical methods. People who have allergic reactions should go to the hospital for diagnosis and treatment in a timely manner.

Anti-allergic precautions

It is not advisable to take a certain type of anti-allergic drug for a long time and in large doses, which easily causes drug resistance. It is advisable to take it for 2 to 3 months, otherwise the efficacy will be reduced, but there will be no dependence. For example, some anti-allergic drugs will Stimulate the body's satiety nerves and produce obesity. After a few days of drug withdrawal, it will recover. Different antiallergic drugs should be taken in turns.

If you need to take medicine for other diseases at the same time, be sure to consult your doctor. For mild drug allergies, families can use anti-allergic medications, but only if they are not allergic to the drug.

For severe patients, multiple anti-allergic drugs can be used at the same time to enhance the efficacy, and the combination of anti-allergic drugs can enhance the efficacy, but you should also consult a professional doctor before combining.

Finally, experts remind that some people will not only be ineffective after taking anti-allergic drugs, but they will allergic. This condition is a sensitization phenomenon of anti-allergic drugs. It is necessary to stop the medication immediately and go to the hospital for treatment in time.