What Is a Bone Marrow Donation?

Hematopoietic stem cell donation (also known as bone marrow donation) is the prerequisite for donation and transplantation of hematopoietic stem cells. Without the donated hematopoietic stem cells, it is impossible to perform hematopoietic stem cell transplantation. Hematopoietic stem cell transplantation technology is currently a more effective and ideal method for treating hematological tumors such as leukemia, lymphoma, and myeloma, and has been continuously promoted in clinical treatment. The incidence of hematological tumors in our country is only about three-thousandths of 100,000 leukemias, which means that there are approximately 36,000 leukemias each year. And most of these patients are under 30 years old, and more than 50% of them are under 15 years old, which brings great burden and misfortune to society and families. Although hematopoietic stem cell transplantation is an ideal method for the treatment of idiopathic tumors, it is not easy to find unmatched hematopoietic stem cells that match the patient's histocompatibility antigen gene.

Bone marrow donation

Hematopoietic stem cell donation (also known as bone marrow donation) is a donation of hematopoietic stem cells

In blood-related people, the probability of matching is one in 10,000. According to China's population policies and conditions, the generation of hematopoietic stem cell transplantation can only be sought from people who are not related by blood. From this, it can be seen that citizens donate

There are roughly: physical and laboratory tests; those who pass the medical examination fill in the relevant forms and sign the voluntary letter of donation; 5 ml are drawn by the staff

Previously donated bone marrow, today donated hematopoietic stem cells. In fact, they are all collected hematopoietic stem cells. The original is to draw bone marrow blood, and bone marrow blood is rich in hematopoietic stem cells, so it was originally called donating bone marrow. Hematopoietic stem cells are now directly collected from peripheral blood, the process is the same as that of ordinary donor blood. Of course, it is necessary to mobilize a large amount of hematopoietic stem cells existing in the bone marrow into peripheral blood. Therefore, the purpose of donating hematopoietic stem cells is to distinguish them from the past and avoid misleading.

(Note the third point, collection method and process: modern

Donation of hematopoietic stem cells will not adversely affect the health of the donor. Many kinds of blood cells in our body come from the same ancestor-pluripotent hematopoietic stem cells. Not only can he continue to differentiate his children and grandchildren, but he can replicate exactly the same cells as himself. As a result, our hematopoietic function is endless. When old blood cells die, new ones grow to replace them; when some hematopoietic stem cells are damaged, healthy stem cells are quickly born to compensate for them. Our bodies work so cleverly. Pluripotent stem cells are not numerous and are distributed throughout the bone marrow. When bone marrow is donated, only a small part of the human bone marrow is withdrawn, and only a part of the pluripotent stem cells is lost. The remaining pluripotent stem cells will quickly replicate, and the hematopoietic function will return to normal in a short time. So donating hematopoietic stem cells will not affect human hematopoietic function.