What Is a Facial Hemangioma?
Facial hemangioma is more common clinically, and is caused by abnormal proliferation of blood vessels. It is a vascular malformation or hamartoma. Most are found shortly after birth. Hemangiomas increase with the growth and development of children. Although some capillary hemangiomas can shrink or spontaneously resolve, generally the growth rate of hemangiomas is faster than the growth and development of children. Affects appearance and facial tissue function. Facial hemangioma is divided into four types: capillary hemangioma, cavernous hemangioma, mixed hemangioma, and hemangiomas according to pathological structure and clinical characteristics. The former two types are the most common.
Facial hemangioma
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- Facial
Facial hemangioma treatment principle
- The second generation of a new type of photosensitizer (Hempofen) is injected into the body through the intravenous route. Hempofen forms a peak in blood concentration immediately after intravenous injection, and is quickly absorbed by vascular endothelial cells, while absorbed by epidermal cells Very few, so the distribution of photosensitizers creates a significant concentration difference between vascular endothelial cells and epidermal cells. At this time, light with a specific wavelength that penetrates superficially and can be selectively absorbed by vascular endothelial cells is given, so that Hempofen produces phototoxic substances such as singlet oxygen, and expands the deformed capillaries in the affected area rich in Hempofen. The vascular network is selectively destroyed, while the normal epidermal layer covering the dilated malformed capillary network is not damaged because it does not contain Hempofen, and the normal deep dermal tissue under the dilated malformed capillary network is shallow and difficult to penetrate due to the laser. Protected by reaching effective excitation. [3-4]
Treatment effect of facial hemangioma
- Previously developed domestic photosensitizers such as YHpD (photoporphyrin) and HpD (hematoporphyrin derivative) are multi-component mixtures, the components are complex, it is difficult to achieve stable and standardized quality control, and the excretion is slow in the body. Use The post-skin photosensitivity reaction lasts for 1 to 3 months, and some patients even last up to 6 months. This brings great inconvenience to the nursing after treatment and the patient's work and life.
- Hempofen (HMME, hematoporphyrin monomethyl ether) is quickly distributed in the body, clears quickly, and is not easy to accumulate, thereby overcoming the main side effect of photodynamic therapy-the persistent phototoxic response of normal tissues. Just a few days. [5]