What Is a Vaccine Refrigerator?

Vaccine cold chain refers to storage, transportation and refrigerating facilities and equipment equipped to ensure the quality of vaccines during the operation of vaccines from vaccine manufacturers to inoculation units.

Vaccine cold chain refers to storage, transportation and refrigerating facilities and equipment equipped to ensure the quality of vaccines during the operation of vaccines from vaccine manufacturers to inoculation units.
Chinese name
Vaccine cold chain
Subject
medicine
Field
Immunology
Application area
Technical term

Status of vaccine cold chain equipment

Because the vaccine is sensitive to temperature, every link from the vaccine manufacturing department to the site where the vaccine is used may fail due to excessive temperature. In order to ensure that the vaccine used in planned immunization has proper refrigeration equipment throughout the entire process from production, storage, transportation, distribution to use, so that the vaccine is always kept under the prescribed cold preservation state, and the reasonable titer of the vaccine is not damaged, China Established a cold chain cooperation project with UNICEF. All counties (districts) in 30 provinces, cities, and autonomous regions nationwide have basically completed cold chain equipment. The supporting equipment of the cold chain includes low-temperature cold storage for storing vaccines, ice freezers, ordinary cold storage, vaccine-specific refrigerated trucks, vaccine transport vehicles, refrigerators, refrigerators, refrigerated backpacks, computers and spare parts.

Vaccine Cold Chain Management System

I. Vaccination is managed by a window and the supply channels are strictly implemented: province-city-county-town-vaccination clinics (vaccination sites). Improve the vaccine distribution and storage system, establish a vaccine distribution account, and the vaccine must match the input and output of the vaccine. The registration must include the name, quantity, manufacturer's name, batch number, expiration date, number of accesses, balance, recipients, notes, etc. .
2. According to the current immunization procedures, formulate a vaccine plan for the total population, birth rate, population of each age group and vaccine depletion coefficient in the area under jurisdiction, and report the number of immunized vaccines for the next year to higher-level disease prevention before March of each year Control agency.
3. The transportation, storage and use of vaccines shall be carried out in strict accordance with the relevant temperature requirements. According to the type and batch number of the vaccine, they should be sorted and arranged neatly. There should be air-conditioning circulation channels between the vaccine cartons (boxes) and the refrigerator freezer walls. Distribute and use vaccines in accordance with the "first short-acting period, then long-acting period" and the same batch of vaccines according to the "first in, first out" principle, storage must be neat, packaging signs are obvious, and air-conditioning circulation channels are left between vaccines.
Fourth, improve the cold chain equipment management system, establish a cold chain equipment account, record the product name, model, arrival time and quantity of various equipment; establish equipment operation and maintenance record book to record the occurrence of failures and maintenance. The vaccine should expire in time to report the damage.
Fifth, the cold chain equipment is managed by special personnel, regularly maintained, and maintenance and temperature records are established. The cold chain equipment must be specially maintained and cleaned frequently. Observe and record the operating temperature in the refrigerator and freezer twice a day (after working in the morning and before leaving in the afternoon); wipe the cold backpack and dry it in time after each use. Return to the freezer in time for freezing.
6. Cold chain refrigerators and freezers should be placed in a dry, ventilated place away from direct sunlight and away from heat sources. There should be space at the rear and shelves at the bottom. Power lines and sockets should be dedicated lines.
7. All planned immune cold chain equipment is only used to store vaccines. No unit or individual may misappropriate. Refrigerators and cold storages that store vaccines are strictly prohibited from storing other items and expired vaccines.

Essentials of vaccine cold chain transportation

Biological vaccines are very sensitive to temperature. Vaccines are special medicines. They have strict requirements for cold storage and heat preservation during transportation and storage. Vaccine is sensitive to temperature. Too high or too low temperature may affect vaccine quality.
Because the vaccine is sensitive to temperature, every step from the manufacturing to the site of the vaccine may fail due to the temperature not meeting the requirements. During storage and transportation, once the temperature exceeds 2 ° C ~ 8 ° C, the vaccine will be destroyed.
Because of the special nature of the vaccine, the storage and transportation conditions are very high. Distribution and storage must be carried out at an appropriate temperature. A complete cold chain cannot be disconnected. If there is a deviation, the vaccine will denature and fail, and it cannot play its due role.
Cold chain broken chain affects vaccine efficacy In the process of transportation and storage, vaccines are limited by conditions. Epidemic prevention agencies below the county rarely have refrigerated trucks, and most use thermos bottles or incubators. It is difficult to avoid high temperature transportation, and sometimes the temperature is high or low , Affecting the efficacy of the vaccine.
Cold-chain transportation requires both soft and hard
During the cold chain transportation of vaccines, special transportation vehicles and temperature monitoring systems are indispensable. Intact hardware is a prerequisite for cold chain transport of vaccines.
To do the cold chain transportation of vaccines, we must first have strong hardware equipment. For example, refrigerated trucks, vehicles and refrigerators must be strictly checked to ensure that they are intact. This is the basis of vaccine cold chain transportation.
The Goods Management Quality Regulations for Drugs clearly stipulates that: Enterprises dealing in vaccines or biological products shall have refrigerated (freezing) storage and transportation equipment suitable for the scale and variety of the business; during transportation, for drugs that require temperature, Corresponding heat preservation or refrigerating measures should be taken; refrigerated vehicles and refrigerated (freezing) boxes used for vaccine transportation should be able to automatically adjust and display temperature conditions; drug transportation should be completed within the prescribed time, and transportation vehicles should not be used as storage locations for drugs .
The entire process of production, storage, transportation, distribution and use of vaccines for planned immunization should have intact refrigeration equipment so that the vaccines are always placed in the specified temperature environment to ensure that the efficacy of the vaccines is not affected. The supporting equipment of the cold chain includes low-temperature cold storages for storing vaccines, ordinary cold storages, vaccine transport vehicles, refrigerators, refrigerators, refrigerated backpacks, and monitoring systems. [1]

Vaccine Cold Chain Related Equipment

Vaccine cold ice pack
1 Disposable low temperature refrigerated ice pack
High density plastic on one side and non-woven on the other
It is mainly used for perishable products, biological preparations and all products that need to be refrigerated (if the technology ice is transported with the product during transportation and cannot be recovered for reuse, it is recommended to use one-time). Although it is designed for one-time use, However, it can also be used multiple times with careful use
2 Reuse cold storage ice packs
It is the longest holding time of all ice products in the world (six times the holding time of ordinary ice of the same volume).
Can be reused N times to save costs. It can be used for both cold and heat. The minimum can be frozen to -190 , and the highest can be heated to 200 . It can be cut at any size and can be in direct contact with food. It is a food-grade technology ice. Safe, non-toxic, environmentally friendly, energy-saving, replaces gel pack, bag ice, block ice and dry ice
Instructions:
First put the ice pack in the water and rub it with your hands to make the technology ice expand. It is best to expand to about 1 cm. After the expansion, take out the surface moisture and dry it, then put it in the refrigerator and use it.
Vaccine refrigerated transport case
Vaccine Refrigerated Transport Box Incubator (3 photos)
It is made of food-grade environmentally-friendly LLDPE material through one-time molding using a rotary molding process. It is equipped with a marine stainless steel lock and a rubber non-slip mat at the bottom. It is non-toxic, odorless, UV-resistant, does not easily change color, and has a smooth surface that is easy to clean. Good insulation effect, not afraid of falling, can be used for life. Continuous refrigerating and holding time can reach several days. It is suitable for long-term refrigerating and fresh-keeping of any item. It is suitable for outdoor leisure activities such as camping, picnics, fishing, rafting, etc .; it can also be used for medical sampling, sampling, biological agent refrigerated low-temperature transportation, Blood transport and more! It can also be used to store items that need to be kept fresh when shopping in the supermarket!

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