What Is B-Type Natriuretic Peptide?
Brain natriuretic peptide, a member of the natriuretic peptide family secreted mainly by the heart, is a polypeptide consisting of 32 amino acid residues. It was named because it was first found in pig brains. Can regulate the homeostasis of blood pressure and blood volume, and diuretic effect.
Brain natriuretic peptide
- Chinese name
- Brain natriuretic peptide
- Foreign name
- Brain Natriuretic Peptide
- Short name
- BNP
- Alias
- B-type natriuretic peptide
- Brain natriuretic peptide, a member of the natriuretic peptide family secreted mainly by the heart, is a polypeptide consisting of 32 amino acid residues. It was named because it was first found in pig brains. Can regulate the homeostasis of blood pressure and blood volume, and diuretic effect.
- Brain Natriuretic Peptide (BNP), also known as B-type Natriuretic Peptide,
- BNP is mainly composed of
- The relationship between BNP and hemodynamic changes has been widely recognized. The plasma concentration of BNP is closely related to the state of cardiac function, and normal BNP concentration can to a large extent deny the existence of impaired cardiac function. A large number of studies have shown that BNP can also be used to diagnose LVD caused by many diseases. However, due to different laboratory conditions, the measurement methods and research methods used are different, and the normal values obtained are different, which needs to be improved. Moreover, it should be noted that BNP is not a specific diagnostic tool, because elevated plasma BNP concentration is not necessarily caused by heart failure. Certain heart and lung diseases, renal failure, liver cirrhosis, etc. can also increase plasma BNP concentration. Clinical data should be combined For identification.
- Despite some limitations, BNP has shown good prospects for the diagnosis, prognosis and guidance of cardiac function. Especially in screening for LVD and risk evaluation after myocardial infarction, it shows obvious superiority. In future applications, strict detection and judgment standards need to be formulated. In short, with the deepening of research, the determination of plasma BNP concentration is likely to serve as an important supplement to assess cardiac function and become a simple and convenient routine test.