What Is Dependent Edema?

Drug-induced edema

Drug edema

Drug edema refers to the disorder of body fluid balance caused by the clinical application of certain drugs, and body fluids remain in the interstitial spaces, causing systemic or local swelling. Drug edema refers to the use of certain drugs, which causes Swelling occurs in some areas. Use of adrenocortical hormones, testosterone, androgens, insulin, thiourea, licorice and other drugs can cause swelling of the face, hands, and feet, and the swelling will gradually disappear after stopping the medicine.

Affected area

whole body

Related diseases

Chibai swim wind edema

Affiliated Department

Other departments

Related symptoms

Hypoproteinemia Ascites Hepatic Edema Anxiety Tense Pelvic Heaviness Breast Swelling Facial Edema Neurological Symptoms Insomnia Weakness Constrictive Pericardial Idiopathic Dizziness Headache Vitamin B1 Deficiency Cardiac Edema Pleural Edema Malnutrition Right Cardiac insufficiency

Drug-induced edema

1. Fasting urine and fasting urine Although it is a common diuretic for the treatment of edema, some women with idiopathic edema may worsen the edema after long-term application of fasting urine. This is because such patients have an increased reactivity of the renin-angiotensity-aldosterone system, and people are prone to edema when standing, and furosemide can aggravate this effect.

2. Insulin administration Drug-induced edema in insulin is mostly at the beginning of medication. Those with mild edema are limited to the lower limbs, and those with severe edema can affect the whole body. Such edema usually resolves within a few days.

3. Indomethacin is an anti-inflammatory drug commonly used for joint pain, neuralgia, and muscle pain. This medicine can inhibit the production of prostaglandins, cause water retention, and cause edema in some people.

4. Chlorpromazines These drugs reduce sodium excretion in the body and cause edema.

5. Glucocorticoid drugs such as prednisone, hydrocortisone, dexamethasone, etc., can directly cause water and sodium retention, and upper body edema obesity may occur after long-term use. In addition, there are drugs such as Xiaoxintong and Xintongding, which can cause edema of different degrees.

Examination and diagnosis of drug edema

Mainly manifested as lower limb or facial edema, severe cases of systemic edema. It is characterized by edema that occurs after medication and disappears shortly after discontinuation. For example, the application of adrenocortical hormone, licorice preparations, androgens, estrogen, calcium antagonists, etc Can cause edema. Edema caused by drugs, as long as the relevant drugs are discontinued, edema can be resolved without causing serious consequences, but it must be paid attention to.

Drug edema confusing symptoms

(1) Cardiogenic edema: In right ventricular insufficiency, exudative or constrictive pericarditis, edema is caused by increased systemic venous pressure and increased capillary filtration pressure. Cardiogenic edema is characterized by edema that first occurs in the sagging area, often from the lower limbs to the whole body, and ascites or pleural effusion may occur in severe cases. Edema develops more slowly. Edema is solid and less mobile. The main basis for the diagnosis of cardiogenic edema is the history and signs of heart disease. Significant increase in venous pressure is an important sign of diagnosis.

(2) Hepatic edema: Cirrhosis often has mild edema in the lower limbs before the onset of ascites, which first occurs in the feet and ankles and gradually spreads upward. Head and face and upper limbs often do not have edema. In severe cases, ascites and pleural effusion occur. The history of various chronic liver diseases and the signs and laboratory indicators of liver damage are the basis for diagnosis.

(3) Malnutrition edema: Chronic wasting disease, chronic nutritional deficiency, protein-loss gastrointestinal disease, severe burns, hypoproteinemia, and vitamin B1 deficiency can cause edema. Tissue relaxation and reduction of tissue pressure caused by reduction of subcutaneous fat will aggravate water retention. Edema often spreads from the feet to the whole body.

(4) Systemic edema for other reasons: Myxedema: Hypothyroidism. When the condition is severe, the skin is infiltrated by mucin and mucopolysaccharide, which results in a characteristic non-depressive edema, called myxedema. It usually occurs before the face and tibia. Drug-induced edema: It can cause edema after application of certain drugs, which is characterized by mild edema after administration of the drug and gradually subsides after stopping the treatment. The more common drugs are adrenocortical hormones, testosterone, estrogen, insulin, etc. Rovolwood, thiourea, and licorice can also cause edema if the dose is too high. Premenstrual tension syndrome is also a common cause of edema, which is characterized by mild edema of the eyelids, ankles, and hands 7 to 14 days before menstruation, which can be accompanied by breast tenderness and pelvic heaviness, and urination after menstruation The amount increased, and edema and other neurological symptoms gradually subsided. Idiopathic edema: mainly manifested in sagging parts of the body, more common in adult obese women, often related to emotional and mental changes, with neurological weakness such as fatigue, dizziness, headache, anxiety, insomnia, etc., the test in the standing position is positive .

Mainly manifested as lower limb or facial edema, severe cases of systemic edema. It is characterized by edema that occurs after medication and disappears shortly after discontinuation. For example, the application of adrenocortical hormone, licorice preparations, androgens, estrogen, calcium antagonists, etc Can cause edema.

Prevention of drug-induced edema

There are drugs such as Xiaoxintong and Xintongding, which can cause edema to varying degrees. Edema caused by drugs, as long as the relevant drugs are stopped, the edema can be resolved without causing serious consequences, but it must be paid attention to.

Edema occurs after administration and disappears shortly after discontinuation. For example, the application of adrenocortical hormones, licorice preparations, androgens, estrogen, calcium antagonists, etc. can cause edema.

Diet should be light and easy to digest, avoid cold, fatty and sea fishy hair. Puffiness and oliguria can be given a salt-free diet; after swelling, a low-salt diet can be given. Those with spleen deficiency and dampness should be given spleen and dampness food. ...