What Is Gardnerella Vaginalis?

Gardnerella vaginalis (GV) was originally a pathogenic bacteria associated with nonspecific vaginitis isolated from vaginal secretions from vaginitis patients in 1954. For decades, domestic and foreign scholars have shown that the bacterium can cause cervical disease, unclean abortion, postoperative infection, urinary tract infection and other diseases. It is a newly recognized pathogen and bacterial pathogen of sexually transmitted diseases. Due to the high nutritional requirements of the initial isolation and culture of this bacteria, it is rare to cultivate in clinical laboratories. The current diagnostic methods mostly use the diagnostic criteria proposed by Amsel et al. In 1983, and some laboratories only perform single experiments.

Gardnerella vaginalis

Gardnerella vaginalis (GV) was originally a pathogenic bacteria associated with nonspecific vaginitis isolated from vaginal secretions from vaginitis patients in 1954. For decades, domestic and foreign scholars have shown that the bacteria can also cause

The causes of Gardnerella Vaginalis (GV) and "non-specific vaginitis" (NSV) and other issues have been reported abroad in recent years. Although the taxonomy and treatment of bacteria have been clarified, the epidemiology of infection, asymptomatic carriers and pathogenic mechanisms need to be further clarified. As early as 1950 LeOPld from patients with prostatitis in men and cervicitis in women. Gardnerella vaginalis was isolated. It is caused by the pathogen Gartnerella and can be transmitted through sexual intercourse. Among people with disordered sexual relations, Gartnerella vaginitis has a high prevalence. Gartnerella-induced infections are more common in sexually active women. Increased leucorrhea, fishy or ammoniaous odor, wet and uncomfortable vulva, often accompanied by vaginal burning sensation, pain during intercourse, and itching of the vulva.

Gardnerella vaginalis (GV) is the causative agent of bacterial vaginosis (BV). Its pathogenicity may be related to the combined action of anaerobic bacteria. In addition to causing BV, GV can also cause premature delivery, puerperal fever, neonatal sepsis, chorioamnionitis, postpartum sepsis, sepsis, urinary tract infections, and kidneys. Abscesses and cystitis. GV is a bacterium with a size of 1.5 2.5 × 0.5m, polymorphism, no capsule, no flagella, and unstable Gram stain. It does not grow on ordinary agar medium, and grows on blood agar medium and chocolate medium, but does not require factor X, factor V and coenzyme. Facultative anaerobic, easy to grow in an environment of sufficient CO2. The optimum growth temperature is 35-37 ° C, and the pH is 6.0-6.5. S-type colonies were -hemolytic. Catalytic enzyme was negative and oxidase was negative. GC2 was 43 ± 1mol%. At present, the media commonly used to isolate GV at home and abroad are: (1) vaginal (V) agar medium, (2) Caseman solid medium, (3) GC chocolate agar medium, (4) (containing Tween 80) double Layered human blood agar medium (BHT), (5) modified human blood agar medium, etc., the identification mediums are: (1) identification medium with caseman basic medium, (2) with GC basic medium Into the identification medium.