What Is Ileitis?

Porcine proliferative enteropathy (PPE) is caused by Lawsonia Intracellularis (LI) infection and is characterized by an adenoma-like proliferation of immature intestinal cells in the ileum and colonic crypt Contact intestinal infectious disease in pigs.

Porcine proliferative enteritis

Porcine proliferative enteritis (PPE) is a common syndrome in pigs caused by a bacterium called Lawsonia intracellularis. There are different names in different literatures, such as necrotic enteritis, proliferative hemorrhagic enteritis, ileitis, local enteritis, and intestinal adenoma disease. The disease mainly occurs in fattening pigs from 6 months to 9 months of age. Weaning piglets and breeding pigs at 2 months of age can also be infected.

The incubation period of this disease is 2 to 3 weeks, and the body temperature is generally normal. Clinically, it can be divided into the following three types:

The small intestine and

1. Mixed herd or herd; 2. Weather stress, such as heat stress or sudden weather changes; 3. Outbreaks of the disease often occur in the remaining herds after the market; 4. Reserve sow adaptation period, or transfer to breeding pigs Soon after herd, this transmission may occur from sows to reserve pigs or from reserve to pass pigs ^[2]

LI mainly affects pigs. The natural infection incubation period is 8-10 days. Breeds introduced from abroad, especially the big white and long white pig breeds and their offspring are more susceptible. PPE mainly occurs in weaned piglets to adult pigs, especially susceptible to growth and fattening pigs at 6-16 weeks of age. The morbidity ranges from 5-40% and the mortality rate is not high, generally 1-10%, but the growth rate is significantly reduced If it causes secondary infection, the mortality rate can be as high as 40-50%. The feces of sick pigs and infected pigs are the main source of the disease. LI can spread through the digestive tract through the feces. Lawson bacteria can multiply in mice, so rodents can be the vector of disease transmission. Therefore, rodent control will help control the spread of the disease. A variety of stress reactions such as turning herds, mixed herds, excessive temperature difference between day and night, too much humidity, too high density, etc .; frequent introductions; frequent vaccination; sudden replacement of antibiotics causing dysbiosis; and immunosuppressive diseases (such as PCV -2, PRRSV); feeding moldy feed; other colitis pathogens that are present on the farm such as Treponema pallidum, Treponema pallidum,

For presumed healthy pigs in the same group that have not yet shown clinical symptoms, flufenicol powder is added to the feed according to the dosage, and the drug is discontinued after 5 days of continuous use, and gentamicin powder is added to the diet for 5 days. Can effectively prevent the occurrence of new cases in the same herd. At the same time, it can also prevent the increase of the morbidity and mortality of the disease due to secondary bacterial infections.
After thoroughly removing the feces inside and outside the pen, disinfect the piggery, pig body, feeding trough, utensils and surrounding environment with disinfectant once every two days until the sick pigs recover. It can minimize the pathogenic microorganisms in the herd, reduce or eliminate the expansion of the herd and the chance of secondary infection.
For patients with clinical symptoms, change to regular water for oral rehydration salts (the formula is 350 grams of table salt, 250 grams of baking soda, 150 grams of potassium chloride, 2 kilograms of sugar, and 100 kilograms of commonly used water) to help increase the body's electrolytes. Maintain acid-base balance, increase disease resistance, and promote growth and development.
After drug treatment, for a few pigs who are still weak, anemic, and have low appetite, 2.5-3 ml of animal serum (containing selenium type) and 4-5 ml of multivitamin B injection are injected once per muscle. It has a good effect on increasing appetite, restoring health, and promoting growth and development.
With the comprehensive control measures mentioned above, the epidemic situation in pigs can generally be controlled and subsided. Pigs that have not yet shown clinical signs in the herd will not show clinical signs; 95% of pigs with clinical signs can recover ^[4] .