What is Interleukin-6?

Interleukin-6, referred to as interleukin 6 (IL-6), is a cytokine and belongs to the category of interleukin. It is produced by fibroblasts, monocytes / macrophages, T lymphocytes, B lymphocytes, epithelial cells, keratinocytes, and various tumor cells. IL-1, TNF-a, PDGF, virus infection, double-stranded RNA, and c AMP can induce normal cells to produce interleukin-6. Interleukin 6 can stimulate the proliferation, differentiation and function of cells involved in the immune response.

IL-6

1. Inducing B cell differentiation;

2.Support

1. IL-6 and IL-1 can synergistically promote T cell proliferation, partly related to the upregulation of T cell IL-2 receptors;

2. It has a synergistic effect on the stimulation of IL-3's multi-directional progenitor cells, and it can also promote the differentiation of B cells;

3. IL-6, like IL-1, participates in inflammation and fever. Some human tumor cells, especially myeloma cells, can secrete IL-6 as themselves.

1. Changes of interleukin-6 and interleukin-10 concentrations in the blood of patients with coronary heart disease

Objective: To investigate the cytokines of interleukin-6 and interleukin-10 in coronary heart disease

Human Interleukin 6 (IL-6) ELISA Kit

This kit is for research use only

Detection range: 15.6 pg / ml-1000 pg / ml

Minimum detection limit: 3.9 pg / ml

Specificity: This kit can simultaneously detect natural or recombinant human IL-6 without cross-reactivity with other related proteins.

Validity: 6 months

Intended application: ELISA method for quantitative determination of IL-6 content in human serum, plasma, cell culture supernatant or other related biological fluids.

Description

1. Kit storage: -20 ° C (when not used for a long time); 2-8 ° C (when used frequently).

2. The concentrated washing solution will precipitate out when stored at low temperature. When diluted, it can be heated in a water bath to help dissolve.

3 There may be inconsistencies between the Chinese and English manuals, please refer to the English manuals.

4 The newly opened enzyme-linked plate wells may contain a small amount of water-like substances. This is normal and does not affect the experimental results.