What Is Sperm DNA Fragmentation?

Sperm DNA fragmentation detection is a process for detecting sperm quality. The degree of sperm DNA fragmentation is considered as a new index to evaluate sperm quality and predict fertility.

Sperm DNA fragmentation test

With the increase of China's industrialization, environmental pollution has gradually increased.

Sperm count, density, activity rate and

Is an important indicator of sperm maturity.

When sperm are damaged, their DNA is denatured into single strands by the action of acid. Acridine orange (AO)

It can emit green fluorescence in the form of a monomer in combination with double-stranded DNA and red or yellow fluorescence in the form of a polymer in combination with single-stranded DNA. Therefore, immature and mature sperm can be distinguished by the intensity of green fluorescence. Sperm with a strength above the main group represents immature sperm with loose chromatin packaging.