What Is Sporotrichosis?

Spores are chronic infections of the skin, subcutaneous tissues, and adjacent lymph systems caused by S. schenckii.

Spores

First, the cause: more history of trauma,
2. Occurrence sites: Exposed parts such as extremities and head and face.
Third, the rash features: subcutaneous nodules or dark red infiltrating plaques, the surface may be mild wart-like hyperplasia, squeeze a little secretion, gradually expand the adhesion to the skin, and spread along the lymphatic vessels.
Fourth, the subjective symptoms: slight.
Fifth, classification: lymphatic, fixed, disseminated.
[Histopathology] Pulmonary inflammation with histiocytic granuloma and neutrophil infiltration. PAS staining in abscesses and multinucleated giant cells can sometimes find spores or stellates.
Experimental inspection Mycelia growth was observed in pus or tissue fungal culture.

First, 10% potassium iodide solution is the first choice of medicine, 10 to 20ml orally for 3 / day, taking medicine after meals, and starting from a small dose, gradually increasing. If the patient can tolerate, treatment should be extended to 4 to 6 weeks after clinical cure.
2. Itraconazole 100mg orally per day for more than one month.
3. Terbinafine 250mg orally for 1 month, for 3 consecutive months.
IV. 5-FC is administered orally at 1.5 to 2 g / day, and can be used in combination with ketoconazole at 200 mg / day for 2 to 3 consecutive months.
Fifth, amphotericin B is suitable for those who are ineffective in the treatment of the above drugs. Intravenous injection can also be formulated into a 0.25% solution for local damage injection.
Local lesions can be considered resection, or physical therapy, hyperthermia or cryotherapy.