What Is Squamous Hyperplasia?

Squamous epithelial hyperplasia, also known as squamous epithelial cell proliferation, is not known in ancient Chinese medicine, but the main itching of this disease can be seen in the description of "yin itching" disease. For the thickening, swelling, and ulceration of the vulva skin during the development of this disease, refer to diseases such as "swollen", "yin pain", and "yin erosion".

Squamous epithelium

Squamous epithelium is a vulvar disease with vulvar pruritus as the main symptom. Any unexplained vulvar pruritus can cause squamous epithelial hyperplasia after long-term scratching and rubbing. It is also clinically called chronic simple lichen or neuropathy. Although other diseases, such as candida vaginal vulvitis, can cause secondary squamous epithelial hyperplasia of the vulva, but because of its clear cause, it can be cured quickly after treatment of the primary disease, so it does not belong to the scope of this disease.

Squamous Epithelial Hyperplasia

Causes of Squamous Epithelial Hyperplasia

Squamous epithelial hyperplasia TCM etiology and pathology

As early as in the chapter "Spirit of Lingshu · Spirit of the Real Evil", "Even among the evil spirits, the people also spread their hairs and become ridiculous. They are deep, struck between the skin, and their qi, Open it up, shake your hair, and move between Qi and Qi, itching. "Sui Chaoyuanfang's" Essays on the Sources of Diseases "states that" ... the evil qi is small, and it cannot be shocked as pain, so itching also. " Yin itching "is the behavior of insects, ... slightly itching, severe pain." It is suggested that the occurrence of itching is related to the evil breath between the skin. The formation mechanism of pain and itching is similar, except that the degree of evil and qi and blood are different. Yin itch develops further.

Squamous epithelial hyperplasia lesions are located in the vulva, and the former was mainly overcast. Traditional Chinese medicine believes that the liver hides blood and its veins surround the vaginal organs; the kidney hides essence and opens the qi from the front and back of the two yin; Chong and Ren Ermai originate from the same cell, and the veins follow the curved bone and upper hair border and pass through the organ. If the liver stagnation, spleen deficiency or dampness and heat of the liver cause endogenous dampness, infusion of coke, damp heat build-up, block impulse, make the genital choroid stagnation, qi and blood run poorly will appear itching, pain, swelling and other symptoms.

1. Liver depression and stagnation. Plain depression, or anger hurts the liver, causes liver loss and drainage, stagnation of Qi, stagnation of responsibility, obstruction of genital veins and blood, and illness. After suffering from this disease, liver stagnation will be aggravated by factors such as inexplicable suffering and husband and wife life, making the condition difficult to heal repeatedly.

2. Damp heat bet. The genitals are inadvertently born and feel the evil of hot and humid; or living in a wetland for a long time, or feeling wet outside, and the heat is turned into heat; or the dampness of the spleen is used to dampen the heat; Water, moisturize, stop, wet and heat together, inject coke under the stream, hurt any belt and under the belt, immerse the vulva. Damp heat builds up, blocks impulse, causes genital choroid stasis, qi and blood loss and causes itching, redness and swelling. If the stasis persists for a long time, or even the stasis becomes unreasonable, skin thickening and pain will occur. The genitals are white due to poor blood flow and loss of nutrition.

3. Kidney deficiency and liver stagnation. Insufficient kidney yin, Qiqing internal injury, liver depression and stagnation. Or liver stagnation for a long time; dark consumption of liver and yin, or liver stagnation and fire, burns yin and blood, so that the liver and blood are depleted, and the kidneys are depleted. The loss of genitals is white and cleft.

Squamous epithelial hyperplasia western medicine etiology and pathology

1. Causes. At present, the exact cause of squamous epithelial hyperplasia of the vulva is unknown. It is generally believed that long-term moist skin and irritation of vaginal discharge may be related to its pathogenesis. In addition, it has been reported that bcl-2 gene protein has been improved in different degrees in the disease, atypical hyperplasia and vulvar cancer.

2. Pathology. The main histopathological changes are hyperkeratosis or incomplete keratinization of the epidermis, irregular thickening of the spinous cell layer, downward extension of the epithelial foot, obtuse or rounded tip, and the tip of the epithelial foot becomes thinner. The dermal papilla between the epithelial feet is obvious, with mild edema and infiltration of lymphocytes and a small amount of plasma cells. However, the epithelial cells were neatly arranged, the polarity was maintained, and the cell size and nuclear morphology staining were normal. ?

Diagnosis of Squamous Epithelial Hyperplasia

Key points for diagnosis of squamous epithelial hyperplasia

1. Medical history. Depressed temperament, or living in a wet place, or taking a large amount of history, or a history of various vaginal inflammation.

2. Symptoms and signs. It can occur at any age, more common in middle-aged women before the age of 50, and it can also occur in old age. The main symptoms are pruritus, which is severe and difficult to tolerate. Due to repeated scratching, the skin damage is getting worse, and itching is more severe. The lesions vary, mainly involving the labia majora, interlabial sulcus, clitoral foreskin, posterior labial union, etc., often symmetrical. When the lesions are mild in early stage, the skin color is dull or gray, and the hyperkeratosis appears white. Due to long-term scratching and rubbing, the skin thickens like leather, the pigment increases, the skin texture becomes prominent, and the skin ridges are raised, showing most small polygonal flat papules, clustered into a patch, and mossy-like changes occur. In severe cases, epidermal damage, cracks, and ulcers can be caused by scratching. If the ulcer does not heal for a long time, especially when there is nodular bulge, one should be alert to the possibility of local cancer. There is usually no atrophy or adhesion.

3. Pathological biopsy. Pathological biopsy is the only diagnostic method. Generally, 1% lidoca should be used; due to local anesthesia, multiple lesions such as erosions, ulcers, indurations, and bulges are selected for multipoint biopsy.

Symptoms of squamous epithelial hyperplasia, in addition to the patient's main complaint, comorbidities, and tongue veins, need to be combined with local signs to distinguish between reality and deficiency.

In general, itching of the vulva, localized rough skin hypertrophy, or hypopigmentation, depression, pulse string, most liver depression; vulvar itching, burning pain, thickening of local skin and mucous membranes, gray or white, or redness around, Rupture, or a lot of carry, yellowish smelly, yellow greasy fur, slippery pulse strings, mostly hot and humid; itching in the vulva area, white color, weakened elasticity, soft waist and knees, depression and discomfort, fine pulse strings Those, mostly for kidney deficiency and liver stagnation.

Squamous Epithelial Hyperplasia Treatment

For the treatment of squamous epithelial hyperplasia, first let the patient keep the vulva clean and dry. It is forbidden to wash the vulva with soap and other irritants. Underpants should use cotton with good ventilation to avoid aggravating the condition. Avoid scratching the affected area with hands or instruments and avoid eating Spicy and irritating food. Then, in controlling local itching, local treatment with corticosteroids is advocated.

And some patients will be used for different diseases: simple vulvectomy, laser treatment.