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Aximus capsules, the indications are primary and secondary hyperlipidemia diagnosed according to Fredrickson classification, namely hypertriglyceridemia (type IV hyperlipoproteinemia); hypercholesterolemia (IIa Type hyperlipoproteinemia); hypertriglycerides and hypercholesterolemia (types IIb, III and V hyperlipoproteinemia).

Aximus capsules, the indications are primary and secondary hyperlipidemia diagnosed according to Fredrickson classification, namely hypertriglyceridemia (type IV hyperlipoproteinemia); hypercholesterolemia (IIa Type hyperlipoproteinemia); hypertriglycerides and hypercholesterolemia (types IIb, III and V hyperlipoproteinemia).

Drug Name

Aximus capsule

Drug type

Prescription drugs, medicines for medical workers' injuries

Use classification

Other vitamin supplements

Aximus capsule ingredients

The main ingredient of this product is aximus, and its chemical name is: 5-methylpyrazolelin-2 carboxylic acid-4 oxide. The chemical structural formula is:

Molecular formula: C ₆ H ₆ N ₂ O ₃
Molecular weight: 154.13

Aximus capsule properties

This product is a capsule and the content is white to slightly yellow powder.

Aximus capsule indication

For hypertriglyceridemia (type IV hyperlipoproteinemia); hypercholesterolemia (type IIa); hypertriglycerol and hypercholesterolemia (types IIb, III, and V)

Aximus capsule specifications

0.25g

Aximus capsules dosage

Oral: 0.25g once, 2 to 3 times a day, after meals. Adjust the dose according to the TG and TC levels, the total daily dose does not exceed 1.2g.

Type IV hyperlipoproteinemia, 0.25 g once, twice a day; Type IIb, III, and V hyperlipidemia, once 0.25 g, three times a day.

Adjust the dosage according to the triacylglycerol and cholesterol levels in the blood.

Acyclovir capsule adverse reactions

Common facial flushing; rare headaches; occasional nausea, vomiting, upset stomach, abdominal pain, diarrhea; very few allergic reactions, rash, urticaria, asthma, hypotension.

The long-term clinical observation of a large number of patients confirmed that the drug is well tolerated. The results of clinical control and laboratory tests show that the drug has no toxic effect on the main parenchymal organs and has no interference effect on metabolic bypass (sugar and uric acid metabolism).
The drug can cause skin vasodilation (redness, hot flashes, and itching), especially in the early stages of treatment.
These symptoms usually disappear quickly within the first few days after treatment.
Gastrointestinal reactions (heartburn, epigastric pain), headache, and asthma are occasionally reported during treatment. Only rare patients need to discontinue treatment due to serious side effects. Very few patients have local and systemic reactions, sometimes severe, that may be associated with immune allergies (eg, rubella, eyelid and / or edema of the lips, rash, asthma-like dyspnea and hypotension). Patients with these conditions should immediately discontinue Le Zhi Ping and take appropriate treatment measures.
The patient should notify his doctor or pharmacist if there are any unexpected reactions not mentioned in the instructions.

Aximus capsule contraindications

Women who are allergic to this medicine, peptic ulcer, pregnant and lactating women.

Notes on aximus

(1) In the case of renal insufficiency, the dose should be adjusted according to the inosine clearance rate. The inosine clearance rate is 80 ~ 40ml per minute, 0.25g per day; 40 ~ 20ml per minute, 0.25g every other day;

(2) Long-term users should regularly check blood lipids and liver and kidney function.

(3) Occasionally flushing and itching of the skin, especially at the beginning of the medication, but continue to take the medication, this phenomenon will soon disappear.

Aximus capsules for pregnant and lactating women

This product is inappropriate for pregnant or suspicious pregnancy and lactating women.

Aximus capsules for children

There is no relevant research data.

Aximus capsules for the elderly

There is no relevant research data.

Aximus capsule drug interactions

No adverse drug interactions were shown in patients taking concurrent antidiabetic or anticoagulant drugs.

Aximus capsule overdose

There are no descriptions of overdose cases in the literature.

Acyclomus capsule clinical trial

There is no relevant research data.

Acyclomus capsule pharmacology and toxicology

Acyclovir inhibits the release of free fatty acids from adipose tissue, reduces the concentration of very low density (VLDL) and low density (LDL) lipoproteins in the blood, and reduces triglycerides and total cholesterol levels.
During the treatment period, acyclovir can have a beneficial effect on HDL cholesterol by increasing its level. The improvement in blood lipids is usually seen in the first month of treatment.
Toxicological studies in various animal species have shown that the drug has low acute toxicity and is well tolerated throughout the body and the gastrointestinal tract during long-term treatment (up to 2 years). Studies on the reproductive system have shown that this drug has no adverse effects on reproduction, embryos or lactation. The drug is not genetically mutagenic.

Pharmacokinetics of aximus

Acyclovir can be completely and quickly absorbed after oral administration. The blood concentration reaches a peak within 2 hours, and the half-life is about 2 hours. This drug does not bind to plasma proteins, is not metabolized, and is excreted from the urine.

Acyclomus capsule storage

Store below 30 ° C.

Aximus capsules

Packed in PVC / aluminum foil, 0.25g per capsule, 30 capsules per box.

Acyclomus capsule expiration date

48 months

Aximox capsules perform the standard

Import drug registration standard JX20000205 ^[1]