What Is Tissue Oxygenation?

The iron in heme is bound to a molecule of oxygen by a coordination bond, and the iron is not oxidized. This effect is called oxygenation.

Oxygenation

Right!

The iron in heme is bound to a molecule of oxygen by a coordination bond, and the iron is not oxidized. This effect is called oxygenation.

Chinese name

Oxygenation

Foreign name

Oxygenation

Organic matter

glucose

Inorganic matter

oxygen

category

chemical reaction

Until the middle of the 18th century, people thought that all nutrients in plants were obtained from the soil, and did not think that plants could get anything from the air. In 1771, British scientist Priestley discovered that placing a lighted candle with green plants in a closed glass cover makes it difficult to extinguish the candle; placing mice with green plants in a glass cover, and mice also Not easy to suffocate to death. Therefore, he pointed out that plants can renew the air. However, he did not know which component of the air the plants had renewed, nor did he discover the key role that light plays in this process. Later, after many scientists' experiments, they gradually discovered the places, conditions, raw materials, and products of photosynthesis. Here are some of the well-known experiments. In 1864, the German scientist Sachs conducted an experiment in which the green leaves were left in the dark for several hours in order to consume the nutrients in the leaves. Then expose half of this leaf and block the other half. After a period of time, the leaves were treated with iodine vapor, and it was found that the half of the leaves that had been shielded from light had no color change, and the half of the leaves that were exposed were dark blue. This experiment successfully proved that green leaves produced starch during photosynthesis.

Neonatal doctors in Switzerland report that keeping newborns under the placenta and delaying umbilical cord clamping until 90 seconds can improve brain tissue oxygenation during the first 24 hours after birth. Dr. Oskar Baenziger and colleagues point out that this technique, called "placental fetal blood transfusion," has been shown to reduce the need for blood transfusion and improve hemodynamic stability in preterm infants. They also wrote in the March issue of Pediatrics (Pediatrics 2007; 119: 455-459.) That increased blood volume is important for cerebral blood flow and oxygen supply, especially in newborns with brain damage in preterm infants. The most important sequelae. Their trial included 39 babies born at the University of Zurich's hospital between 24 and 32 weeks of gestation. Fifteen babies were randomly assigned as the experimental group and 24 as the control group. The authors explained that the babies in the test group were born immediately after the mother had used oxytocin. The babies born by cesarean section were placed 15 cm below the placenta. The babies were delivered as low as possible and the umbilical cord clamp was delayed by 60 to 90 seconds. In the control group, the umbilical cord was clamped within 20 seconds. At 4, 24, and 72 hours, clinical data showed higher hematocrit in the experimental group (55% versus 49%). At 4 hours, infants in the test group showed higher arterial blood pressure and a higher propensity for oxygenated hemoglobin values. In these newborns, local tissue oxygen saturation is higher at 4 and 24 hours. Brain oxygenation is assessed by measuring deoxyhemoglobin, oxyhemoglobin, total hemoglobin, and local tissue oxygen saturation using a near-infrared spectrometer. Researchers estimated that the placental fetal transfusion group had higher brain tissue oxygenation at all three time points. Dr. Baenziger and colleagues concluded that a higher brain oxygenation reserve in the experimental group may reduce the risk of hypoxic-ischemic events in the brain. ^[1]

Twenty-one patients with acute exacerbation of COPD who were hospitalized were selected to monitor and record the blood pressure, heart rate, respiration, and SpO2 observations at different time points of oxygen inhalation in the initial semi-recumbent position, prone position, and reversion to semi-recumbent position.

Oxygen inhalation at different periods and in different supine positions has little effect on the vital signs of the patient; the changes in SpO2 are statistically significant. When the prone position is reverted to the semi-recumbent position, SpO2 is maintained at a slightly higher level in the initial semi-recumbent position.

The gas exchange improved in the prone position, SpO2 increased, and the gas exchange weakened, and SpO2 decreased when returned to the supine position.

Monitoring and nursing patients who are prone to oxygen in the prone position should pay attention to the following points: observe the changes in the patient's blood pressure, heart rate and blood oxygen saturation; the method of turning over and supporting the pad should be correct to avoid compression of the chest, abdomen and bone joints, and the patient's head Raise 15 ° ~ 30 °; keep the airway open. ^[2]