How Do I Choose the Best Antihistamine for Hives?
Cold urticaria is the most common form of urticaria in physical urticaria and can be seen at any age. There are two kinds of familial and acquired. The former belongs to autosomal dominant inheritance, which can be affected after birth or early years, and can last a lifetime. The latter is more common in young women. The disease is characterized by pruritic edema and wind mass in the cold area after contact with cold water or other icy substances, which can disappear in about half an hour to about one hour. It is more common in exposed areas such as the face and hands, and other areas may be affected in severe cases. Edema, or even abdominal pain, can occur in the cold mucous membranes of the mouth, tongue, pharynx and other cold foods or cold drinks.
- English name
- coldurticaria
- Visiting department
- dermatology
- Common locations
- Occurs on exposed areas such as face and hands
- Common causes
- Family inheritance, acquired
- Common symptoms
- Pruritic edema, wind mass
- Contagious
- no
Basic Information
Causes of cold urticaria
- There may be two reasons for the onset of cold urticaria: it has the characteristics of familial inheritance, and it is possible that the parents of the patient have such a disease and passed it on to the next generation; For example, patients stay up all night, low immunity due to moderate fatigue, or decreased immunity due to some diseases.
Clinical manifestations of cold urticaria
- Cold urticaria is a type of urticaria, and its clinical manifestations are mainly itching and wind masses in different parts of the body when exposed to cold conditions. Skin lesions can be confined to exposed areas or areas in contact with cold objects under cold conditions, or they can spread and affect the oral mucosa, even as headaches, chills, diarrhea, and tachycardia. There are many opportunities to contact cold objects in winter, so this disease is easy to see.
Cold urticaria treatment
- Eliminate the cause
- Eliminate the cause, often need to apply antibiotics when there are infections, should be avoided when allergic to certain foods. Chronic infections are often the cause of chronic urticaria.
- 2. Antihistamines
- Although antihistamine drugs cannot directly counteract or neutralize histamine and prevent the release of histamine, they have a scramble effect on histamine and can quickly suppress the generation of wind masses. Antihistamines have various side effects. It is best to choose those with fewer side effects. Long-term use of one antihistamine can easily cause drug resistance, and another can be used. Or alternate or merge applications. Children are more resistant than adults, so their relative use is also greater.
- (1) Antalol (hydroxyzine) can be selected for its good stability and antihistamine effect, and has good effects on artificial urticaria, cholinergic urticaria and cold urticaria.
- (2) Epinephrine and aminophylline can increase the CAMP in mast cells and inhibit the release of histamine, which can quickly promote the elimination of wind mass or edema of acute urticaria or giant urticaria, especially aminophylline and antihistamines are used in combination or Synergistic effect with epinephrine, especially for patients with asthma or abdominal pain.
- (3) 6-aminoacetic acid can be used for cold urticaria and giant urticaria, atropine or profenoxine and chlorpromazine can be used for cholinergic urticaria.
- (4) Calcium can be used in the treatment of chronic urticaria with acute urticaria, reserpine, and anoxemia.
- (5) Steroids are used in severe acute urticaria and serum urticaria. Small doses can be used for stress urticaria and complement-activated urticaria. Urticaria complicated by anaphylactic shock is even more necessary.
- 3. Topical application
- Calamine lotion or zinc oxide lotion can achieve temporary effects.
- 4. Vitamin C supplementation
- An effective method to cure urticaria has been proven in practice.