How effective is amitriptyline for depression?

The use of amitriptylin for depression has been common since the medicines have been developed and sold in 1961. Over the years, many studies have shown that amitriptylin is at least as effective for depression as other tricyclic antidepressants and newer selective serotonin reurculation inhibitors (SSRI). Amitriptylin works by reducing reabsorption with nerve cells of serotonin and norepinephrine, neurotransmitters that play a role in mood regulation. This increases the duration and concentration of neurotransmitters in the brain and relieves depression by prolonging the duration of positive moods. This may take several weeks of taking medication before the maximum results are observed. Initially, it was generally believed that the use of amitriptylin for depression was ineffective for most types of depression. During the 1950s, sales were poor until more research revised the effectiveness of amitriptyline for depression, especially in cases where depression is very serious or lasted long. Medicines also help with child underset, hyperactivity disorder and schizophrenicy symptoms. This discovery has led to the use of amitriptylin to treat many other conditions. It is still the most commonly used tricyclic antidepressant due to its efficiency, low costs and ability to help improve simultaneous conditions.

Although the efficacy of amitriptylin for depression has been well known, some people cannot tolerate unpleasant side effects of the drug such as drowsiness, weight gain and a grim head. Adverse reactions, especially daily drowsiness, generally Diminish over time and for many people become tolerable. Others who suffer not only from depression but insomnia, migraine or other conditions have the fact that amitriptylin can also help these conditions. This is especially true because people suffering from depression tend to have problems with insomnia and anxiety.

Newer class antidepressants such as SSRI and SNRI have become commonly prescribed and maybe they are more known than TricykLicky antidepressants such as amitriptylin due to less and less serious side effects. Doctors also believe that these drug classes are more effective than amitriptylin, despite research that suggests that they are equally effective. Some doctors believe this could be the result of marketing society, because these newer drug classes are often more expensive than older tricyclics.