How Effective Is Naproxen for Arthritis?

Naproxen has anti-inflammatory, antipyretic and analgesic effects, and is a PG synthase inhibitor. For rheumatoid arthritis and osteoarthritis, the effect is similar to aspirin. For patients who cannot tolerate anti-inflammatory and analgesics such as aspirin, indomethacin, etc. due to anemia, gastrointestinal system disease or other reasons, this product can obtain satisfactory results, while suppressing platelet effect is small.

Basic Information

Drug Name

Naproxen

Whether prescription drugs

Non-prescription drugs

Main indications

Rheumatoid arthritis, gout

Dosage form

powder

Athletes use with caution

Use with caution

Whether to include health insurance

Incorporate

For rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, chronic degenerative diseases of the motor system (such as joints, muscles and tendons) and mild to moderate pain such as dysmenorrhea.

Oral: 200mg / time, 2-3 times / day. Children take 10mg / kg daily in divided doses.

It is mainly mild and temporary discomfort in the gastrointestinal tract. Manifested as nausea, vomiting, indigestion and constipation; rare insomnia or drowsiness, headache, dizziness, tinnitus, pruritus, rash, angioedema, visual impairment, prolonged bleeding time, decreased granulocytosis, gastrointestinal bleeding, dyspnea, Liver and kidney damage and mental depression. This product has been thought to be well tolerated for a long time, but a clinical study found that taking this product at a regular dose has a higher risk of cardiovascular and cerebrovascular events than the placebo control group.

Those who are allergic to aspirin are forbidden to use it, and those with history of peptic ulcer or peptic ulcer should be used with caution. Because other non-steroidal anti-inflammatory drugs can cause fetal arterial ducts to close prematurely, and because it can inhibit prostaglandin synthesis, it can cause dystocia or prolonged labor, so pregnant women should not use it unless there is another reason. The concentration of this product secreted into milk is equivalent to 1% of the blood concentration, and it is not suitable for lactating women. Long-term medication should be regularly checked for liver, kidney function, blood and eye examinations.

(Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.)